We are delighted to announce the opening of registration for the Ninth Conference of the Calorie Restriction Society International! The Conference will be held May 18-21 at the Hilton Tucson East in Tucson, Arizona, close to the University of Arizona’s main campus. Come join your fellow CR Society members to learn the results of cutting-edge CR science. Interact directly with key researchers in the fields of CR, metabolism, and the retardation of aging. Learn more from scientists and fellow prac
CR causes weight loss, including loss of muscle, and young CR animals have much less muscle than young animals allowed to eat all they want without becoming fat. But as the animals age, the CR animals hold on to their muscles much better, and the cellular and molecular structure of that muscle remains intact, so that in old age the CR animals have as much or more muscle as the conventionally-fed animals and are actually stronger. Dean Pomerleau breaks down a new study highlighted by James Cain t
It's not surprising that people who are overweight and obese benefit from reducing their Calorie intake to shed the excess fat tissue. By contrast, it's more than a little counterintuitive that Calorie restriction is also beneficial to animals (and possibly humans) who are already lean to begin with. In animal studies, CR is one of only a very small number of interventions that actually slow down the degenerative aging process, and its "anti-aging" benefits kick in exactly starting from the poin
Most rodent CR experiments use very severe CR that humans can't tolerate. Lifespan studies suggest that the extension of healthy life is proportional to the degree of CR, starting from a mouse colony's characteristic nonobese baseline. A series of studies in posted in this week's Weekly research updates by CR Society Board member James Cain drills down into the anthropometric and metabolic effects of graded doses of CR, and the parallels (or not!) of equivalent levels of protein restriction. Plu
At the May 31 Board Meeting, the CR Society Board of Directors elected Michael Rae and James Cain as new Board members. Michael is a long-time CR practitioner, current VP for Research, and previous member of the Board; James is Assistant Professor of Biology at Aurora University. President Brian M. Delaney offered ex officio support for their election at the June 14 meeting. Congratulations and welcome!
The scientific journal Cell, an extremely high-impact journal in basis mechanisms of metabolism, has a Special Issue on "The Biology of Food" that includes a lot of papers of interest to people practicing CR. See the CR Society Forums for a selection →
CR Society International President was recently interviewed for the SAGE Science of Aging blog of the Buck Institute for Research on Aging. The Buck Institute is one of the most prominent and productive private research laboratories working on discovery and intervention in the degenerative aging process, exploring the roles and potential of diet, genetic manipulations, stem cells, and other factors in aging and anti-aging.
The CR Society International is pleased to announce that we have appointed Michael Rae as CR Society International's new Vice President for Research. Most of you will know Michael as a long-term CR practitioner and contributor to the List and Forum. Michael was also a member of the Society's Board for several years. Michael is heavily steeped in the science of CR, as well as the broader field of aging research. As most of you know, he is also Science Writer at SENS Research Foundation, a biomedi
On a recent CR Way teleconference, Dr. Stephen Spindler discussed his milestone paper:
Review of the literature and suggestions for the design of rodent survival studies for the identification of compounds that increase health and life span.
Doctor Spindler suggests exacting standards for how longevity studies should conducted in mice. Hopefully diligent researchers who seek outcomes that are truly accurate will integrate Dr. Spindler’s suggestions into their studies.
The CR Society Intl and the CR Way are working together to support CR research. For every CR Society member who becomes a CR Way member, the CR Way will contribute 20% of the membership fee to the CR Society for research.You can learn more by visiting the LivingTheCRWay Store: Store.LivingTheCRWay.com.
Since its beginning, The CR Way has strongly supported the Society, encouraging its growth and fostering its meetings. Now supporting the Society research has become urgent:Blood has
Our recent visit to the Spindler Lab in California was extraordinary. Have you ever talked with someone whose words were so profound that they affected you for years or perhaps even your whole life? I felt that happening to me at a recent meeting with Dr. Joseph Dhahbi who explained his vision for analyzing the effects of calorie restriction on aging at the cellular level. Never have I heard so comprehensive a vision for thorough analysis of cell signaling as it relates to CR's health benefits.
Calorie restriction has changed! Eleven years ago, we were in the dark ages. People knew little about how Calorie restriction works and the CR world was dominated by demagogues who tried to shove piecemeal research down the throats of new CR members or anyone else gullible enough to listen.
So we rolled up our sleeves and went to work. Money needed to be raised and CR research was desperately needed on humans.Now, 12 years later, science has prevailed. We know that human CR follows the