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  2. Discussions of Spirulina go waaaaayyy back to my early days on the CR List. Indeed there were several discussion threads devoted to the product. IIRC, there were also several active Spirulina users at the time -- myself included (have not used it, however, since 2004/5). A few recent product spotlights have re-sparked personal interest. According to this video ... --- Also, just received an email from Methuselah Foundation with subject "Deep Space Food Challenge Phase 2 Opens". Have no idea what this is about or whether spirulina is being investigated. https://www.mfoundation.org/news/deepspacefoodphase2opens I think cryptocurrency is involved! So good for MF!
  3. Today
  4. Guffer

    CR for elderly 80+

    Hi Saul, Thanks for that tip. Shows they're on the right track. Kind regards, Geoff.
  5. Podcast all platforms + Show Notes: https://livelongerworld.substack.com/p/bkennedy
  6. Mike41

    Are we exercising too much!

    https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2788473 here we see a new published study showing lowered mortality and improved quality of life using accelerometer data over a long period of time. This study indicates a plateauing around 60 minutes a day, but the QOL and mortality figures continue to improve. Indication: The more exercise the better!
  7. I won't dispute that. That's exactly how I exercise. I also set the resistance level to be near the maximum -- to accomplish some skeletal muscle strengthening as well. -- Saul
  8. alexthegra8

    Are we exercising too much!

    Would anyone here dispute the claim that a high quality elliptical machine is the most superior, accessible form of cardiovascular exercise because of its low impact on joints? Swimming is apparently "the best" but it takes more resources (either travel or good weather) to do regularly.
  9. alexthegra8

    Getting back into Exercise post COVID

    Thanks a lot for the support. Even as a person w/ an advanced degree and one that is well versed in a lot of health literature, I still think the media has done A LOT of harm in scaring people over covid. Lots of my colleagues at work (that fall into the demographic you describe) are terrified of the virus and sensationalize it greatly.
  10. not everyone who catches Covid shows symptoms of Long Covid. Remember, we live in the obesity epidemic. People with obesity and/or diabetes are much more likely to have severe problems with covid. any study that doesn't adjust for comorbidaties isn't very useful. If you're in good health, but have recovered from mild covid infection, I wouldn't worry much about Long Covid. I'd go back to at least 30min of aerobic exercise, say about 5 days a week (or more), and maybe a bit of stengthening. Good luck (and looking to work out tomorrow myself - but I've never had covid), -- saul
  11. Yes. But it's a sample of just one. (I sometimes call it a "one rat" study). BUT, I'd love to come close to his lifespan. (No surprise that he lives (lived) in Japan.) -- Saul
  12. Yesterday
  13. "The risk of rare side effects from COVID-19 vaccines like AstraZeneca are greatly exaggerated as they are far safer than many medicines people are taking every day" "Around 11 per cent of older Australians take daily aspirin to help prevent stroke and heart attack, but statistically, aspirin is two hundred times more dangerous than AstraZeneca – resulting in around one death per 10,000 people." Getting a COVID jab is safer than taking aspirin https://pursuit.unimelb.edu.au/articles/getting-a-covid-jab-is-safer-than-taking-aspirin
  14. "Doctors have discovered an “antibody signature” that can help identify patients most at risk of developing long Covid, a condition where debilitating symptoms of the disease can persist for many months." Long Covid: doctors find ‘antibody signature’ for patients most at risk https://www.theguardian.com/society/2022/jan/25/doctors-find-antibody-signature-long-covid
  15. COVID has finally infiltrated my nervous system. 32 male, 67kg, 176cm, in shape. I had fever on Friday night / Saturday day (maximum 101.0), then fatigue, cold chills, night sweats, -- it seemed like a light version of the flu. By Monday I felt pretty well and worked at my job full capacity. I think omicron may be "nature's vaccine" - a very light illness. Yet, I am seeing conflicting information about getting back into exercise. Myocarditis and COVID-19 | How Exercise Affects COVID-19 (bicycling.com) Exercise and Athletics in the COVID-19 Pandemic Era - American College of Cardiology (acc.org) There is a lot of scary stuff out there about heart/lung damage after covid, how exercise can cause it, exacerbate the illness, then even re-install it. A lot of information recommends people to go and get full EKGs and other cardio tests before even trying exercise after covid...this seems quite overblown to me? Does anyone have any general advice as to how to ease back into exercise? My routine was usually 30 minutes of cardio a day (cycle/jumprope) + 10x10 kettlebell swings (and one other weight lifting exercise). Thanks in advanced,
  16. Maybe I could have explained it more clearly. Even a virus is a complex structure that is not infectious without its exact structure being intact. After recovery from an infection, there may be viral "body parts" around, including viral RNA, but the PCR result identifying the remnant RNA would be insignificant. If you find a human skeleton, examine its bone marrow and find human DNA, it does not mean there is a live person. Most people getting tested are symptomatic and then getting a positive PCR test is meaningful to distinguish the infection from say the flu. Infectious virus quickly is lost after someone recovers.
  17. COVID-19 blamed for greatest drop in life expectancy in Canada since 1921 https://www.cbc.ca/news/canada/life-expectancy-covid-decrease-1.6326089 >>>>>>>>>>>>> Pandemic was 3rd leading cause of death in 2020 in Canada The Canadian Press · Posted: Jan 24, 2022 "That made COVID-19 the third leading cause of death in Canada in 2020, though Statistics Canada added that the pandemic may have also contributed indirectly to a number of other deaths across the country." "Some countries, including Spain, Italy and the United States saw greater impact on life expectancy from the pandemic, with declines up to 1.5 years."
  18. Sibiriak

    Muscle mass and heart disease

    I'm so friggin' cynical! Lol! I'm sticking with elderberry wine for now!
  19. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2788244 urolithin A is a supplement that appears to be beneficial for cell mitochondria by slowing muscle deterioration with age. Urolithin a is natura substance found in berries and wine. Findings In this randomized clinical trial of 66 older adults, those who received supplementation with 1000 mg of urolithin A had a significant improvement in muscle endurance (number of muscle contractions until fatigue) for both hand and leg skeletal muscles compared with those who used placebo. Plasma levels of several acylcarnitines, ceramides (biomarkers of mitochondrial health), and C-reactive protein were decreased after urolithin A supplementation.
  20. Mandiepands

    Sudden stop in weight loss

    @DeadStarsStillBurn I was just wondering if you decided to maintain around 60g protein per day for your weight loss as you mentioned in the first post, or if you decided to go back up to around 100g? Also, would love to hear how this has been working for you since these posts in September - for example how your progress is going in terms of weight loss weekly/thus far; if you have continued to make any more modifications to your diet and how those have been going. Thank you!! - Amanda
  21. A PCR test is used to detect simply the presence of viral genetic material in an individual. So how is a PCR test result the " final product of what the body does or does not do to fight the virus"?
  22. What the heck does this prove? People go in to be tested for virus because they are sick, i.e., have replicating virus. This study looked at recovered patients, who had no symptoms and found what was probably surviving remnants of virions and showed most could not replicate. People who were infected and recover assume they are not carrying actively replicating virus and do not bother testing for what are in almost all cases viral RNA remnants. So do not look under rocks for replicating virus, as almost every infected person does after recovery, and it will never matter at all.
  23. Last week
  24. Mike Lustgarten

    Supercentenarian (112 - 116y) Blood Test Analysis

    Thanks Ron. Jiroemon's CRP was great at 111.5y, but not great afterwards. In contrast, his glucose, HbA1c, TGs, and HDL were consistently good, which suggests greater importance for those variables on longevity.
  25. Another exceptionally informative TWIV episode on the hypercomplex world of immunity. What happens after a RNA vaccine is injected, how the immune system evolved and optimized to prevent death but not infection, I'll have to listen to it another 2-3 times. First few minutes as usual spent in idle conversation, then John Yewdell dives full speed into a world which is still in part unknown.
  26. Yes, since at that time he was following the keto narrative and, weird as it sounds, vegetables were considered unnecessary accessories.
  27. Alan, no, it's not so simple, the immune system did not evolve to decrease the number of positive PCR tests, it evolved to prevent death and serious disease, infection is a very natural occurrence which no vaccine, except the HPV vaccine, can effectively prevent so far on the long term. When personal freedom and community public health clash, common sense should prevail. Trying to persuade skeptics by reasons and proper communication methods, not by force. At the end, in many countries like Italy even before the mandates about 80% of people were double vaccinated. The dictatorial methods radicalized the behavior of no-vaxxers, they shook the beliefs in the democracy of many citizens, me including. Hospital occupancy could have been improved after the first wave. I believe it's taken as an excuse of government incompetence, even as the no-vaxxers are presently constituting a scapegoat for the inadequacies of government policies. At the end, the no-vaxxer takes its own risks, the vaccinated population is sufficiently protected, there would be no need to make a fuss about it.
  28. Hi Ron! I think you're much too negative in your opinions about Al Pater. Al probably has the best background in biology of anyone on this List, with the possible exception of Michael Rae. Concerning Peter Attiya -- I've never thought much of his opinions. -- Saul
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