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  1. Today
  2. Not a big surprise. That definitely is a side effect of the stress of the pandemic, that effects a large part of the population. Many people are afraid to go to a hospital when they need care. It doesn't mean that the pandemic isn't real. IMO, the best solution is to get everyone fully vaccinated, including young children (5 years and up -- hopefully younger ones, soon), and to get booster shots. Best vaccines appear to be Pfizer and Moderna. -- Saul
  3. The media settin' the story for the tragic vax side effects that are a comin'? You be the judge: Up to 300,000 people facing heart-related illnesses due to post-pandemic stress disorder, warn physicians https://www.standard.co.uk/news/health/post-pandemic-stress-disorder-heart-conditions-covid-london-physicians-b969436.html Ahem ... PPSD ... yup ...
  4. Yesterday
  5. Probably yes on masks when outside, COVID or not: https://www.washington.edu/news/2021/08/04/fine-particulate-air-pollution-associated-with-higher-risk-of-dementia/ Ha, we'll all look like Daft Punk eventually
  6. Well.... I think we would agree, that this study really doesn't support any vast conclusions. Just to be clear: I believe that the worst possible nutrition decisions can't be compensated by some longevity drug. If you are morbidly obese and severely overfed on a particular macro-nutrient and/or given a particular damaging form (2 kg pure sugar/fructose instead of 2 kg of complex carbs every day) no amount of rapamycine will be able to rescue your health. Still, it would be interesting to see actual mortality data or at least disease burden/progress instead of just a few biomarkers. The current design really doesn't allow comprehensive conclusions (let alone for humans), but are merely hypothesis forming.
  7. Last week
  8. Quote from the study “strong positive correlation between dietary protein and mitochondria, generating oxidative stress at high protein intake” no details on this in the article. Has anyone read the full article
  9. Todd Allen

    Nutrition and longevity drugs

    It looks like they focused on calories and macro nutrient ratios but not food quality. Although it is hard to quantify food quality my experience is it deserves more attention. I wonder to what degree research findings would remain relevant in a context of less processed higher quality foods.
  10. U.K. study finds mRNA COVID-19 vaccines provide biggest booster impact Pfizer and Moderna give large antibody, T-cell boosts, study finds Thomson Reuters · Posted: Dec 03, 2021 https://www.cbc.ca/news/health/covid19-vaccine-pfizer-moderna-booster-study-dec2021-1.6272140
  11. Covid: First data points to Omicron re-infection risk By James Gallagher Health and science correspondent The first real world data showing the coronavirus variant Omicron may evade some of our immunity has been reported by scientists in South Africa. https://www.bbc.com/news/health-59520945
  12. Sibiriak

    Nutrition and longevity drugs

    Thanks. Some further details in this Science News article: Diet trumps drugs for anti-aging and good metabolic health
  13. Implying that a boost-booster may be soon after required...
  14. I don't know if this article has been cited elsewhere in the forum, it appears to be very interesting, although it's a mice trial. Basically it says that diet is a more powerful tool than metformin, resveratrol and rapamycin are in improving longevity (based on benchmarks in the liver of mice...). I still have to read the whole. https://www.sciencedirect.com/science/article/abs/pii/S1550413121005283?via%3Dihub#:~:text=Nutritional reprogramming of mouse liver proteome is dampened by metformin%2C resveratrol%2C and rapamycin
  15. A human monoclonal antibody potently pan-neutralizes SARS-CoV-2 VOCs by targeting RBD invariant sites Promising new research.
  16. Odds of Testing Positive for SARS-CoV-2 Following Receipt of 3 vs 2 Doses of the BNT162b2 mRNA Vaccine. Patalon T, Gazit S, Pitzer VE, Prunas O, Warren JL, Weinberger DM. JAMA Intern Med. 2021 Nov 30. doi: 10.1001/jamainternmed.2021.7382. Online ahead of print. PMID: 34846533 Abstract Importance: With the evidence of waning immunity of the mRNA vaccine BNT162b2 (Pfizer-BioNTech), a nationwide third-dose (booster) vaccination campaign was initiated in Israel during August 2021; other countries have begun to administer a booster shot as well. Objective: To evaluate the initial short-term additional benefit of a 3-dose vs a 2-dose regimen against infection of SARS-CoV-2. Design, setting, and participants: This preliminary retrospective case-control study used 2 complementary approaches: a test-negative design and a matched case-control design. Participants were included from the national centralized database of Maccabi Healthcare Services, an Israeli healthcare maintenance organization covering 2.5 million members. Data were collected between March 1, 2020, and October 4, 2021, and analyses focused on the period from August 1, 2021, to October 4, 2021, because the booster dose was widely administered from August 1 onward. Exposures: Either 2 doses or 3 doses of the BNT162b2 vaccine. Main outcomes and measures: The reduction in the odds of a positive SARS-CoV-2 polymerase chain reaction (PCR) test at different time intervals following receipt of the booster dose (0-6, 7-13, 14-20, 21-27, and 28-65 days) compared with receiving only 2 doses. Results: The study population included 306 710 members of Maccabi Healthcare Services who were 40 years and older (55% female) and received either 2 or 3 doses of the BNT162b2 vaccine and did not have a positive PCR test result for SARS-CoV-2 prior to the start of the follow-up period. During this period, there were 500 232 PCR tests performed, 227 380 among those who received 2 doses and 272 852 among those who received 3 doses, with 14 989 (6.6%) and 4941 (1.8%) positive test results in each group, respectively. Comparing those who received a booster and those who received 2 doses, there was an estimated odds ratio of 0.14 (95% CI, 0.13-0.15) 28 to 65 days following receipt of the booster (86% reduction in the odds of testing positive for SARS-CoV-2). Conclusion and relevance: Previous studies have demonstrated that vaccine-derived protection against SARS-CoV-2 wanes over time. In this case-control analysis, we showed an association between receipt of the booster dose and a reduction in the odds of testing positive for SARS-CoV-2, potentially counteracting waning immunity in the short term. Further monitoring of data from this population is needed to determine the duration of immunity following the booster.
  17. Good news for authoritarians and big pharma? EU must consider mandatory Covid jabs, says Von der Leyen
  18. COVID-19: Some Omicron cases have 'mild' symptoms and experts should know more about transmission 'within days' - WHO I'm pretty sure this is the typical progression of deadly fast spreading diseases and something similar happened over time with the flu. So this alledgedly very fast spreading "Omicron" may actually be very good news.
  19. If he had very high Ldl from genetics diet would not fix that. I know about this first hand familial hypercholesteremia runs in my family and it killed my father at 44 and many others.
  20. No Severe COVID Cases Among Vaccinated Patients Infected With Omicron, Top Israeli Expert Says
  21. BrianMDelaney

    Best source for nuts

    Hi everyone. A warning about nuts.com. They are now shipping nuts in bags that have little "serration"-like holes to make it easier to tear open the bag. (True at least for the one-pound bags of macadamia nuts I just received.) This means the bags are not air-tight. Really irritating. Brian
  22. Yep, I considered including that data in the video, but opted for the all-cause mortality instead. Nonetheless, it's an important finding!
  23. Maybe Finnish BeanIt and pulled oats count as low-PDCAAS proteins!! https://www.beanit.fi/en/ they are a less complete version of protein than soy/tofu is, and may be more filling than most food!
  24. Earlier
  25. Omicron symptoms mild so far, says South African doctor who spotted it Dr Angelique Coetzee, the South African doctor who first spotted the new Covid variant Omicron, says the patients seen so far have had "extremely mild symptoms" - but more time is needed before we know the seriousness of the disease for vulnerable people. Watch her tell the BBC's Andrew Marr how patients in South Africa have told her they've been feeling. BBC News https://www.bbc.com/news/av/uk-59450988
  26. https://www.beanit.fi/en/ OMG this is so incredibly healthy and barely increases my blood glucose.
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