Insufficient vitamin D speeds aging. It increases mitochondria damage, inflammation, & loss of proteostasis. Vitamin D regulates thousands of genes & many pathways, affecting eg: klotho, NF-κB, Nrf2, SIRT3, TNFα, & more. Known in 2019 & before: https://t.co/Ge6gH6c4E3
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— Karl Pfleger (@KarlPfleger) May 7, 2021