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Cloud

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  1. Hi everyone, have you seen this recent video by Dr. Fontana just on the use of fructose? https://www.youtube.com/watch?v=EZRzQKY9sbc
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    Dr Joel Fuhrman's approach

    I have read that book too and i liked it, but the title isn't a little misleading? From a scientific point of view is not proprerly correct saying that some foods can improve immunity. The proof on human beings I think are still non conclusive.
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    Edited

    Hello Mechanism, nice matches! I suggest to you also to try this line: http://onedropzen.org/
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    Edited

    Hello Mechanism, sorry for my late replying to your kind email. I have not so much time unfortunately. My nickname comes from my interest in zen where often there is a reference to 'cloud'. a term used to name monk is 'unsui', literaly cloud-water. I don't remember how I did find the dr.Klapper video, but is the best thing on fasting I found. he and Dr.Goldhamer work at the same center and they have a lot of experience on fastings. Luigi Fontana group has started a collaboration with them to collect their data on fasting to be analized. all the best!Cloud
  5. Hello, you will have for sure noticed the last publlished study by Tomasetti and Vogelstein. I report below the Luigi Fontana'scomment on his facebook page, I think it is very interesting. there was a question if it is preferible for limiting the cellular proliferation a daily caloric restriction or also a weekly caloric restriction as consequence of 1 or 2 days of fasting He answered that we don't know still but he thinks it is better the daily caloric restriction and also that if you eat a lot after or before fasting this could bring to a paradox effect.... all the best, Cloud ‘BAD LUCK’ WITH RANDOM DNA ERRORS IS RESPONSIBLE FOR TWO-THIRDS OF CANCER MUTATIONS, STUDY SAYS Sensational article on the Los Angeles Times commenting incorrectly the results of a very nice work published in SCIENCE by Cristian Tomasetti and Vogelstein. http://www.latimes.com/…/la-sci-sn-cancer-bad-luck-20170323… http://science.sciencemag.org/content/355/6331/1330 In reality, Cristian (with whom I spoke) did not say that most cancers are due to "bad luck" and that there is nothing to do. What he observed in this study is that most replicative mutations (i.e. unavoidable errors associated with DNA replication) that lead to tumors occur in highly proliferating stem cells. The higher the rate of proliferation, the greater the risk of mutations that develop into cancer. How can we reduce the risk of random mutations? By lowering the rate of cell proliferation! How can we lower the rate of cell proliferation? By reducing calorie intake and performing regular endurance exercise (both together), which in turn reduce levels of growth factors (e.g. insulin, IGF1, testosterone, estradiol, inflammatory cytokines, leptin) that accelerate cellular proliferation and the risk of random mutations! Moreover, the reduction of these growth factors with calorie restriction inhibits the insulin/IGF pathway, which through FOXO upregulates DNA repair genes. This is the reason why caloric restriction in animal models is the most powerful intervention in preventing cancer! MEDITATE AND TAKE ACTION!
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    Edited

    Hello, do you know this video of Dr. Klaper on fasting? https://www.youtube.com/watch?v=m92Y12lpl6Y&t=2056s
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    Mimicking fast-mimicking diet?

    Hello, prof. Fontana here https://m.youtube.com/#/watch?v=wOns29hNaWs Offers his point of view about many questions. He does not reccomend FMD at the moment, because the data are mostly on animals and it is needed that independent groups do tests on humans . McCoy maybe you can translate more easily than me ...
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    HIIT book recommendations

    Trump is a good example of world turned upside down.... Fontana told that he is working on the english edition, but it will take time (I had the impression that he is translating the book personally). The Longo's book was written in English by him and translated in Italian by a translator, I think that the english edition will be pubblished soon, Anyway I think that most of the people here know and practise most of the content of the books. but they can be important and relevant for the majority of other people.
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    HIIT book recommendations

    Just a few days ago Luigi fontana published a great book named "la grande via" , in it He analyze 1) nutritions 2) exercises ( also HIT training and yoga and tai chi) 3) meditation , especially mindfullness. There are also a chapter about nutrition for children and another on ecology and impact of our choices on the world. Really great view . I appreciate his intention more than Longo's.
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    Edited

    I tried recently to follow an IF of 16:8 type, skipping breakfast. I did for about 10 days, at the end I got used but 1) I noticed that I eat more in lunch and dinner and was more difficult to control the consumption of fruit 2) I was not able to continue to do the weekly fasting of 36 hours I do usually. So I decided to stick to my usual plan of eating three times a day and having one a week 36 hours fasting. very interesting the information about possible conflicts between tea and anti oxidants. In the FMD by Longo I noticed the use of hibiscus tea, but in some part hte information is contradictory, because I read also that he suggested to not drink coffee etc. I use to take curcuma pills in low doses, maybe I will dismiss the use of it before and during fasting. thank you.
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    Sleep thought of the day

    I have a question about hormesis. It is a concept proposed by Mattson and we think that it is one of the cause of benefits of Exercise, Fasting,Cold exposure, Caloric restriction, etc. But I wonder how much it has been verified experimentally, like for example the autophagy, it could be that hormesis is a very nice principle but nevertheless not explaining everything.... what do you think?
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    Sleep thought of the day

    here are some studies recently cited by Luigi fontana on the importance of a good sleep, I haven't read them, but maybe are interesting: 1)Sleep drives metabolite clearance from the adult brain. https://www.ncbi.nlm.nih.gov/pubmed/24136970 2) Sick and tired: Does sleep have a vital role in the immune system? http://www.nature.com/nri/journal/v4/n6/full/nri1369.html 3) Sleep promotes branch-specific formation of dendritic spines after learning. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447313/ 4) And on the converse: Sleep, circadian rhythms, and the pathogenesis of Alzheimer disease. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351409/ Sorry for the bad format, but here is night, I have still to finish some work before going to bed,... t0o late :-)
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    studies from China

    I am a big fan of Chinese culture, so do not get me wrong if I link this article, which I find interesting and worrying: https://health.spectator.co.uk/fakery-massive-scale-means-just-cant-trust-studies-china/
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    Cronometer results for the FMD

    I have to say that the week following the FMD diet days I have more difficulty to limit what I eat, especially dark chocolate and fruits... Mccoy, I plan to follow FMD diet only three times a year, the rest of time I do a 32 hours of water fasting a week. all the best, Cloud
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    Cronometer results for the FMD

    Hello Mccoy, here is the link to the vegetable soup available in Italian store here: http://www.catalogoprodotti.coop.it/pam/it/Categorie-PAM/Alimentari-freschi/Verdura/Verdura-preparata/vellutata-di-verdure-Biologica-620-g/p/7215516 I supposed that complex carbohydrates like whole brown rice cakes are allowed, the first time I tried FMD I based on the recipes provided freely by Josh on his blog on aging. ciao!
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