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  1. drewab

    Is David Sinclair a hypster?

    While you may arrive at the conclusion that you don't think what he's saying lives up to the hype and that the science doesn't pan out (or will not pan out), it is factually incorrect to say that he sells any supplements including resveratrol, NAD, NR, and so forth. If you actually spend any time following his work you will realize that this is made abundantly clear again and again and again...
  2. SOS stands for salt, oil, and sugar. That is certainly one definition of health, but to me, the absence of illness doesn't suggest the possibility of thriving and living a great life (as difficult as that may be to define). Having said that, it would be difficult for some people to thrive when experiencing illness. The WHO has a different stance on health and states: Health is a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity. I noticed Alan that you didn't attempt to answer my question though. What do you think - is a vegan diet healthier than eating meat and dairy?
  3. To me, the question could be further refined. I think it's clear that for most individuals a diet with generous quantities of animal products (even organic and wild-caught) is not as optimal as a whole-food plant-based diet that is free from refined products, added sugar, oils, and salt. I do wonder about how it compares to a diet that is quite similar but that contains say 5% of calories from animal products, but that still contains 50-100g of fiber daily and a wonderful spectrum of plant foods. I doubt the difference is large either way, so it probably doesn't matter. I personally eat a nearly exclusive WFPB diet that is free from refined products, is virtually SOS free, and is nearly entirely organic. I've had very extensive bloodwork and cardiovascular workups and it seems to work very well for me. I've had no deficiencies come up in the 10+ years I've been doing this and I currently supplement with vitamin D and vitamin B-12. Intermittently I supplement with magnesium, zinc, and a few other items, but those 4 are the ones I have taken more regularly. So Alan, to answer your question, I suggest you evaluate your own metrics of health and arrive at your own conclusion. What's your answer? (Even if it's just speculation or based on your own experience).
  4. The guy has dishes out $100 million, what have you done to contribute other than another negative post on the CR forums? It seems to be your default response these days.
  5. In all of the perusing I've done pertaining to longevity, I hadn't yet come across Sergey Young. He has a book appropriately titled "Growing Young" that is soon to be released. His website is here: https://sergeyyoung.com/ His $100 million dollar longevity fund is of interest as well as his X-Prize involvement. I think this conversation will be much appreciated by folks here.
  6. drewab

    Starting a CR Diet

    I wouldn't worry about the question you are asking too much, nor would I advise fasting (though if you really want to do it, please do it medically supervised). There are so many things you can do that will vastly improve your health and position you much closer to your goal weight: Each plenty of whole plant foods including vegetables, fruits, nuts, seeds, whole grains, and legumes (if a particular food item doesn't work for you, then don't eat it). Some high-quality animal proteins are permissible if you'd like in small amounts - I personally have none and this makes it very easy to maintain a BMI of 20.7. Get some vigorous movement 5-6 days per week - jog, lift weights, swim, bike, do yoga, etc... whatever you like and find sustainable. Perhaps 20-30 minutes most days. Additionally, get a lot of NEAT - non-exercises activity thermogenisis. My step count is typically 15000-20000 due in large part to NEAT (don't sit too much and try to be constantly in motion). Practice TRF (time-restricted feeding) - eat all of your calories in a given window of say, 6-10 hours, but work your way up to it. Don't consume any sugar or processed foods, for obvious reasons. Don't consume alcohol (or limit it greatly, to say 1 drink per week maximum). Practice stress reduction - maybe this means meditation, connection with loved ones and friends, time in nature, etc. It will look a little different for each person. Supplement intelligently, if at all. The exact supplements will vary depending on your diet and goals. Get bloodwork done and a thorough evaluation to see how you are truly doing with your health. Stress the body in other ways - cold exposure, activate heat shock proteins, etc. Lastly, December is about 30 weeks away and I wouldn't try to lose more than 30-60 pounds by then. I think this is entirely doable if you stick to the above.
  7. I can't offer any constructive thoughts other than to say keep up the great work! These videos are fascinating and I enjoy watching them. While I'll likely never apply the same level of rigor to my lifestyle that you employ, there are some takeaways that I keep in mind with my simpler regime. Your analysis is sort of like watching an Olympian do their thing compared to someone with a general interested in fitness.
  8. I get up to pee once a night more or less every night. I’ve been doing it for so long that it’s practically unconscious at this point and I fall back asleep nearly instantly. I think it comes with the territory of eating a diet rich in plants (probably 6-7 pounds daily) and with virtually no added sodium. For a period of time I restricted all fluids within a few hours of bed and also included salt about 3-4 hours before bed in the form of hot sauce. This seemed to allow me to retain water overnight and not have to get up to pee. Ultimately I decided that the extra sodium was not worth it (it moved my intake from 400mg a day to 1000-1500mg or so). I think it’s remarkable how clear my pee is on an exclusive WFPB diet without any refined products. Prior to eating this way I was focused heavily on animal products and I did not experience this (though I had a plethora of other health issues).
  9. Hi cTpa, I think that your question is an interesting thought experiment and I believe it will lead to some interesting discussion in this thread. I was seriously ill (not from cancer) and did a complete 180 in my lifestyle just over a decade ago. On that note, if you are interested in reading about it you can do so here as I recently composed a long piece on 10 years of a WFPB (mildly CR'd) lifestyle: https://www.drmcdougall.com/forums/viewtopic.php?f=1&t=61699 To be clear about one thing, I eat a lot of food and in some ways may live more of an 'exercise-induced CR' lifestyle than being a true CRON-ie. Having said that, my bloodwork looks remarkably similar to those adhering to more conventional CR with more normal exercise regimes. Basically, a health crisis early in my life resulted in me going WFPB, engaging in exercise, cold exposure, heat exposure (sauna, steam room, etc.), taking up a meditation/mindfulness practice, tinkering with intermittent fasting, spending a great deal of time in nature, and so forth. Basically, if it's a longevity practice with robust data around it, I try to engage in it. I don't think a great deal would change if I were to get diagnosed with cancer as I think I've probably optimized a lot of what can be done. Having said that, I would almost certainly book a trip to True North Health Center for a medically supervised water-only fast as an intervention. As McCoy mentioned, doing regular rounds of Longo's FMD is probably something I would look to incorporate on a monthly basis. I would research the hell out of whatever condition I had and I also try to make peace with the fact that the outcome may be out of my hands (which I'm sure is easier said than done). I would also quit my job, spend every moment I could with family and friends, and try to see as much of this incredible world as I could. And if I was fortunate enough to survive, then I would resume working and contributing to society once again. I also would very seriously consider conventional medical treatment and would probably take advantage of it in some form. I'm certainly pro-medical establishment and think that an uber-healthy lifestyle is complementary to whatever current standard of care may be in place. The type of cancer, age of diagnosis, survival rates, and so forth, would undoubtedly influence my decision making though. If I was diagnosed with stage IV pancreatic cancer, it would be much different than to be diagnosed with early-stage prostate cancer. I appreciate Dean's openness in sharing his experience here.
  10. I hear you - I have a similar issue but there are a few that I have found that I can tolerate. For example, I can tolerate chickpeas and lentils well (cooking in the Instant Pot seems to make them much easier on the guy). But meanwhile there are many other common legumes that I don't do well with (i.e. kidney beans).
  11. I continue to enjoy your videos Mike! I've noticed that legumes, lentils, and other pulses are notably absent from your diet. Any reason in particular?
  12. I actually make my own hot sauce and I'm not concerned about lead/heavy metal contamination (from a manufacturing point of view at least), though I suppose theoretically some of the ingredients I use could be grown in contaminated soil. Spices are a pretty broad category, so I guess it would depend.
  13. Well, I found part of the answer here from 2015, though I'm not sure if your diet has changed since then? Either way, it looks great to me!
  14. I really enjoyed this video Mike. It's quite interesting to see how your 2006-2013 values compare to your 2015-2020 values. Congratulations on improving your kidney function in a clear and measurable way. I've also got to commend you on your 25 servings per day of vegetables! I had to listen to it twice since for a moment I thought that the 2000/g per day might include all whole plant foods, but it certainly sounds like pure veg to me! Have you ever posted your complete diet anywhere? I would be very interested in taking a look. By the way, your kidney values towards 2006 were the worst included (though certainly comparable to average). Why do you think there weren't as good then?
  15. drewab

    Oldest Man 111

    This thread prompted me to look up some of the ages of the longest currently living people. Kane Tanaka is currently the oldest verified person at 118 and is from Japan. More on her can be found here: https://en.wikipedia.org/wiki/Kane_Tanaka What I find remarkable is that unlike many centenarians who were seemingly healthy right up until the end, she clearly is not. It is remarkable to think that she had pancreatic cancer at age 45 and is still alive today. The 10-year survival rate for pancreatic cancer is less than 2% and here she is 73 years later still alive.