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BrianA

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  1. lol, ok good luck with that New CDC data shows the risk of dying from Covid-19 is 11 times higher for unvaccinated adults than for fully vaccinated adults https://www.cnn.com/2021/10/15/health/cdc-covid-risk-higher-unvaccinated/index.html
  2. Ivermectin: How false science created a Covid 'miracle' drug https://www.bbc.com/news/health-58170809
  3. The anonymous meta-analysis that’s convincing people to use ivermectin https://arstechnica.com/science/2021/09/the-anonymous-meta-analysis-thats-convincing-people-to-use-ivermectin/
  4. BrianA

    CR for those with two ApoE4 alleles?

    Possible already existing drug that may help ApoE4 carriers: "The analysis showed that those who had the genetic risk and took bumetanide had a ~35% to 75% lower prevalence of Alzheimer's disease compared to those not taking the drug." Precision medicine data dive shows diuretic pill may be viable to test as Alzheimer's treatment https://www.sciencedaily.com/releases/2021/10/211011110815.htm
  5. I wouldn't use chickenpox or measles as a model for developing expectations regarding durability of immunity post-covid infection. A better idea is to model those expectations after the behavior of the human body to similar coronaviruses. Here is a recent study that did just that, using various parts of the sars-cov-2 virus, and finding the most similar other viruses, and then developing a range of expected reinfection probability, which to sum up is: "Reinfection by SARS-CoV-2 under endemic conditions would likely occur between 3 months and 5·1 years after peak antibody response, with a median of 16 months. This protection is less than half the duration revealed for the endemic coronaviruses circulating among humans" So unless you want to risk getting reinfected every 16 months on average, strongly consider an annual vaccination/booster. The durability of immunity against reinfection by SARS-CoV-2: a comparative evolutionary study https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(21)00219-6/fulltext
  6. No, your antibodies are not better than vaccination: An explainer https://arstechnica.com/science/2021/10/prior-infection-vs-vaccination-why-everyone-should-get-a-covid-19-shot/
  7. Mice modified to express human ACE2, used for studying sars-cov-2, demonstrate significant 24.4% bone loss and osteoclast increases even in mild disease cases: Osteoclast-Mediated Bone Loss Observed in a COVID-19 Mouse Model https://pubmed.ncbi.nlm.nih.gov/34607050/
  8. Public space UV disinfection may be possible: Specific UV light wavelength could offer low-cost, safe way to curb COVID-19 spread https://www.sciencedaily.com/releases/2021/10/211004115142.htm
  9. Part of why some people have longer symptoms seems to be related to unusual micro-clots: Inflammatory micro clots in blood of individuals suffering from Long COVID https://www.sciencedaily.com/releases/2021/10/211004104134.htm
  10. For anyone unvaccinated, it looks like you can expect to get reinfected over time, again and again: For unvaccinated, reinfection by SARS-CoV-2 is likely https://www.sciencedaily.com/releases/2021/10/211004104303.htm
  11. Sars-cov-2 appears to affect adiponectin production from fat cells: COVID-19 may trigger hyperglycemia and worsen disease by harming fat cells https://www.sciencedaily.com/releases/2021/10/211001130233.htm
  12. twitter thread reviewing recent evidence that vaccination beats natural immunity due to prior infection, in regards to breakthrough reinfection risk:
  13. HEI study in Europe finds evidence of health effects at lower levels of air pollution https://www.greencarcongress.com/2021/09/20210925-hei.html "The shape of the associations with natural cause mortality showed steeper slopes at lower exposures, with no evidence of concentrations below which no associations were found for PM2.5, BC, and NO2."
  14. I don't understand so far the extremely lackadaisical attitude organizations of all types seem to be taking towards the concept of air filtration. Why aren't schools, businesses, government buildings, etc retrofitting UV air sterilization and improved filtering into their ventilation? Here's a recent study showing on how much incredible improvement in air safety can be achieved via relatively simple and straightforward means. " Airborne SARS-CoV-2 was detected in the ward on all five days before activation of air/UV filtration, but on none of the five days when the air/UV filter was operational; SARS-CoV-2 was again detected on four out of five days when the filter was off. Airborne SARS-CoV-2 was infrequently detected in the ICU. Filtration significantly reduced the burden of other microbial bioaerosols in both the ward (48 pathogens detected before filtration, two after, p=0.05) and the ICU (45 pathogens detected before filtration, five after p=0.05). " https://www.medrxiv.org/content/10.1101/2021.09.16.21263684v1.full.pdf
  15. As Florida punishes schools, study finds masks cut school COVID outbreaks 3.5X https://arstechnica.com/science/2021/09/as-florida-punishes-schools-study-finds-masks-cut-school-covid-outbreaks-3-5x/
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