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Everything posted by BrianA

  1. BrianA

    Exercise Effects

    Have you tried replacing some of the running with an elliptical machine? Seems lower impact.
  2. BrianA

    Coffee Revisited

    So it appears you might want to not use "pods" or a french press to make your coffee, instead stick with filters: Filtered coffee helps prevent type 2 diabetes, show biomarkers in blood samples https://www.sciencedaily.com/releases/2019/12/191219214147.htm
  3. I eat some foods like Kind Bars that have a bit of chicory root added, now I'm questioning if that's a good idea? Curious what comments everyone has: Gut Bacteria Link Dietary Fiber with Liver Cancer https://www.genengnews.com/news/gut-bacteria-link-dietary-fiber-with-liver-cancer/
  4. BrianA

    TMAO & Cardiovascular Disease

    Lifelong choline supplementation ameliorates Alzheimer’s disease pathology and associated cognitive deficits by attenuating microglia activation https://onlinelibrary.wiley.com/doi/full/10.1111/acel.13037
  5. Dean (or anyone), do you have any thoughts on Mary Lou Jepsen's startup Open Water - she has been promising BCI via non-invasive infrared hologram tech.
  6. BrianA

    Back to CE but...

    Sometimes my nose just runs from being exposed to cold air. Happens often if I go mountain biking in colder weather.
  7. BTW, the Flumist nasal version of the vaccine is back to being available again. They tweaked one of the target strains in it to make it more effective. An option for those of us who prefer to avoid any preservatives+adjuvants that might be in the injected vaccine. Also for us cheapskates, I found the local Publix is giving away $10 gift cards for getting the vaccine. ?
  8. Interestingly, a new gene therapy in testing to permanently produce more FGF21 protein seems to cure T2D/obesity in mice. https://www.sciencedaily.com/releases/2018/07/180709104608.htm
  9. BrianA

    Certificate error

    Yeah there are even various projects to make installing them easier. Here's one: https://certbot.eff.org/
  10. BrianA

    Certificate error

    To the site admin: you can get a free certificate through https://letsencrypt.org/
  11. I like to sprinkle some of this Seitenbacher-brand seasoning on my veggies, very salty and tastes good: https://www.amazon.com/Seitenbacher-Vegetarian-Vegetable-Seasoning-5-Ounce/dp/B000FAPM2Q
  12. Randomly ran across this today, describing (if I'm understanding it correctly) how mitochondria actually reconfigure themselves based on the prevailing glucose vs. fatty acids fuel source availability. Body has all kinds of tricks like this we're still figuring out. https://www.ncbi.nlm.nih.gov/pubmed/27052170
  13. Well let us know how it goes with your normal food. However I would say that last year when I did an extended water-only fast for the first time, I also experienced some elevated glucose readings afterwards. However it was hard for me to decipher as at the time I was using a slightly unreliable meter combined with happening to just switch to a fresh set of test strips after the fast, and on top of that over-eating calories for a few days after the fast. It did seem that after 4 or 5 days my readings settled down. Part of the issue may be just how much of your body can fat-adapt to feed off ketones. May take a little while for it to switch back to glucose?
  14. By the way for anyone using the TrueResult glucose meter, I discovered mine is affected pretty heavily by temperature. About a month ago I was experimenting with letting the house temp drop down a lot during the night, to around 60 F. And I had my meter+strips stored in the coldest area of the house, a closet near an air vent, so they probably were dropping into the 50's F. So I noticed my morning readings were suddenly going up quite a bit, 10 to 15 points. Once I started setting the house temp back to a fixed 72 F, problem solved.
  15. Wondering: does anyone combine heat exposure with CE? "Frequent sauna bathing can reduce the risk of dementia, according to a recent study carried out at the University of Eastern Finland. In a 20-year follow-up, men taking a sauna 4-7 times a week were 66% less likely to be diagnosed with dementia than those taking a sauna once a week." https://scienceblog.com/490745/frequent-sauna-bathing-protects-men-dementia/
  16. I do chinups and pullups on a $20 contraption I bought at Walmart several years back. Check their fitness section. It just sits on top of the trim board going across the top of a door. So if you have a doorway you don't mind leaving open all the time, and that has a trim board running across the top, this probably will work. It doesn't screw into the trim or anything, so no permanent attachment.
  17. BrianA

    The Singularity May be Closer than It Appears

    Hanson is flexible enough to consider arguments from the other sides, in fact he was recently awarded a grant to work on a follow-up style book to Em that will focus on "what if AGI comes before Ems", perhaps that book will be out around 2018. He does lay out some explanation near the beginning of Em why he thinks WBE will come before made-from-scratch AGI. Curious what you think once you get hold of a copy.
  18. BrianA

    The Singularity May be Closer than It Appears

    Cool stuff. Just finished reading Hanson's The Age of Em - the scenario tackled in it is what might happen if emulated human brains happen before we have "hand coded" AGI. One way he suggests for us soon to be unemployed humans to stay rich (for a while, until we squander it one way or another) is to invest in tech companies. I guess based on this deep learning research, one good area to invest in might be GPU manufacturers. High powered GPUs would also be in demand in an "Em" style economy.
  19. PGC-1 alpha boosted in gene therapy mice slows AD progression https://www.fightaging.org/archives/2016/10/pgc-1%ce%b1-gene-therapy-slows-alzheimers-progression-in-mouse-model/
  20. The recently discovered hormone irisin helps brown fat, and also reduces atherosclerosis. http://news.ufl.edu/articles/2016/09/exercise-releases-hormone-that-helps-shed-prevent-fat.php https://www.ncbi.nlm.nih.gov/pubmed/27355581 And it seems to be released in higher quantities in higher intensity exercise. https://www.ncbi.nlm.nih.gov/pubmed/24910199
  21. Fat cells that amplify nerve signals in response to cold also affect blood sugar metabolism https://www.sciencedaily.com/releases/2016/09/160930130522.htm
  22. How cancer’s 'invisibility cloak' works https://www.sciencedaily.com/releases/2016/09/160926111323.htm Loss of IL-33 allows cancer to evade immune system. Since CE increases IL-33, does that make it cancer-protective?
  23. https://www.sciencedaily.com/releases/2016/09/160928083216.htm Brown adipose tissue is able to secrete factors that activate fat and carbohydrate metabolism
  24. BrianA

    The Singularity May be Closer than It Appears

    There is some work being done (actually going back to Y2K funnily, when MIRI was founded) on AGI safety by a few groups at this point. This area has really taken off in the past 18 months or so. A few: https://intelligence.org/ https://www.fhi.ox.ac.uk/about/mission/ http://www.openphilanthropy.org/focus/global-catastrophic-risks/potential-risks-advanced-artificial-intelligence/uc-berkeley-center-human-compatible-ai https://openai.com/ Still a ton of work to be done, this is not an easy area of research and I feel is still underfunded in comparison to the coming impact of AGI. P.S. Y'all might enjoy Robin Hanson's new book The Age of Em. He's working on another one for next year from the perspective of AGI coming before human emulations.
  25. Ahh, darn I'm CT on rs1421085. No wonder I up until recently I was the one who always wanted the thermostat set warmer. After forcing myself to do CE for a while now, I'm pretty much over that though. Looking forward to winter!