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  1. If Bill Gates invested any money he should ask for a refund........he looks very old. Bezoar ain’t looking that good either.
  2. If most all your blood is still in your body, you feel rested and relaxed , then you are good to go. Forget worrying about anything else.
  3. There is some groundbreaking research being done by myself. This is the real thing, but I can’t disclose my final results due to legal reasons and patent protection concerns. What my lawyers tell me I’m able to release is that it concerns a flavored concoction of Vanilla and other assorted ingredients. I have dubbed this substance, “COOKIES AND CREME”. And again my lawyers are only allowing me to release preliminary findings......... Fat, I’m getting fat.
  4. DHL

    Walking and All-Cause Mortality

    And a corollary to this research is that people that eat regularly tend to live longer. Currently scientists are researching if regular breathing promotes longevity, but the jury is still out.
  5. I’m not a practitioner of CR. In fact I’m very fond of ice cream and pizza. But I’m guessing that some CR fans might be reversing course and possibly putting on pounds at the moment.
  6. None of that stuff above is going to help you. It’s just going to help the people that SELL it to you. Also the reason that things like ibuprofen are probably bad if and when you get the infection is because it reduces immune response. My plan is to hopefully get a small amount of virus and get infected soon if I’m not already infected, so I can develop antibodies against the infection. I’m in my fifties but in good health with low blood pressure. PS........ It might be time for anyone that purposely severely restricts their calorie intake to reverse course and have a pint of ice cream .
  7. Sinclair’s only interest is selling crap. The only person that benefits what from Sinclair’s is Sinclair, his bank account.
  8. Why take any supplements at all ? If you want calcium.......pizzza, cheese, ice cream, milk. Vitamin D..........Sun. Simple, Easy, Natural, and SAFE.
  9. When you get old blood vessels, the heart, body tissues all get stiff............. Maybe the key to extended longevity is somehow imparting cellular “flexibility” to the circulatory system. Yeah, probably impossible.
  10. DHL

    Jeanne Calment was a fraud?!!

    I wholeheartedly believe from the evidence and arguments I have seen and heard, that Calment was a fraud.
  11. DHL

    Who would live longer?

    I believe the answer is a U shaped curve. The 5% body fat isn’t healthy, and 40% fat isn’t healthy. Common sense says ideal is 15% to 25% long term, IMO.
  12. Is anything at all proven about extending life span ? Because Aubrey needs something fast ! Personally I think aging and survival is not getting something fatal and for your heart and blood vessels to be flexible for a long time.......probably more genetics than anything else. PS..........the theory of Jeanne Calmet faking her age is very believable.....
  13. Hi, my name is David and I am new to the forum, and I have a somewhat novel (I think) twist on extreme longevity. What if extreme longevity was actually caused by defective genes and epigentic changes. Some in response to a harmful environment. Take the theory of George Williams and antagonistic pleiotropy, that what makes us our strong youthful selves, actually contributes to our coming apart as we age—————- My possibly unique insight is that defective and or suboptimal genes and necessary epigentic changes as we age, can in some cases lead to extreme longevity. I postulate that unusually long life spans are due to NEGATIVE and somewhat harmful mutations present from birth, and others due to epigentic changes to a harsh environment. There was a recent study that survivors of the nuclear bombs dropped in Japan actually lived longer, (maybe survivor bias ?). Also male concentration camp survivors lived longer then men not subjected to that horrific experience. Again, maybe survivor bias ? But still very interesting. From an evolutionary standpoint extreme longevity is irrelevant, as it only benefits the individual, but does almost nothing to help future generations survive, and multiply. Now let’s say that an individual that is born with suboptimal genes for immediate survival and fitness is born and due to good medical care, nutrition, and parental care, manages to survive and thrive, but to a lesser extent then their cohorts. What if the early life and young adult defecits turn out to delay for the most part..........cardiovascular disease and susceptibility to cancer. So those genes in the right combination..............That while reducing fitness in youth and during reproduction actually help delay deleterious effects of aging. 1) Extra flexible tissues (but not too flexible), heart, blood vessels, skin..........while being disadvantageous at 18 years old, are actually ADVANTAGIOUS at say 78 years old and beyond......as hardening of the arteries is mostly delayed. This would weaken tissues such as skin, muscles and bone compared to like aged cohorts in youth. But cause these tissues to remain more flexible as one ages. Thereby preserving greater function into old age. (Note: look up Tenascin X deficiency and cardiovascular protection theory.) 2) And the mutations that cause people to be less suspetable to growth hormone. Maybe they can’t get as big and strong in their youth, but maybe that adds to their hearts ability to function as they age. As their heart isn’t as susceptible to hypertrophy and becoming less efficient, as quickly as their more typical cohorts. Again, maybe certain mutations and epigentic changes while making the organism suboptimal in its reproductive prime, could be responsible for extreme longevity. This might mean that extremely old people instead of having mostly superior genes to survive into extreme old age, actually have that right combination of genes that while not the most beneficial in early childhood and in their reproductive prime, BUT RATHER had mutations and genes that were not harmful enough to compromise their survival, while lessening their fitness at an earlier age, and paradoxically EXTENDING their life span due to mutations and epigentic changes. Like having a more flexible heart and blood vessel. More resistance to growth hormone, etc. So while these people didn’t grow as big and strong as their cohorts earlier in life, they were still able to survive...........and yet possibly not “grow” old as quickly as their cohorts due to genes that slightly reduced their fitness earlier in life, to INCREASE their fitness later in life due to not showing equal signs of wear and tear. Also note that some centenarians had few or no children. i think healthy habits and common sense might someone live till say 75 years old in good health. But living till 100 or 110 and beyond is doubtful to be greatly influenced by just diet and exercise. I think you either need to be born with these beneficial changes that while detrimental in early life, however benefit survival later in life. Or somehow change your biology later in life with medical technologies that haven’t been invented yet, to mimic the suboptimal effects early in life that some people have, which are possibly the reason for their delayed aging. Thanks for letting me express my theory even if no one agrees with it. Would like to hear feedback. Best, David (53 year old male with more than a few mutations)