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Ron Put

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  1. Hah, it wasn't hard: https://en.wikipedia.org/wiki/Caucasian_honey_bee Beneficial for beekeeping[edit] Gentle and calm on the comb Longest proboscis, so it can extract nectar from the deepest nectar tissues, where no other species can Ardent brood production – raising strong colonies Colonies reach full strength in mid-summer, which is good for areas where the highest nectar flow is in mid-summer Very great user of propolis In its native area a better honey producer than the European dark bee Not beneficial for beekeeping[edit] Colonies do not reach full strength until mid-summer, which is an undesirable trait for areas with the highest nectar flow in the spring. The great use of propolis may be seen as undesirable as it makes hive management more difficult. Frames and hive boxes are glued together more substantially. Over-wintering in northern climates is not good due to susceptibility to nosema. Inclined to drifting and robbing
  2. I deem it to be basically sugar, but since my biome test, I decided to amp up my probiotic foods intake, thus my search for answers on honey. AIPater had posted a little study on honey and its CV benefits: I figure a couple of jars a year won't hurt, so I ordered some buckwheat honey ( Goshen Honey Amish Extremely Raw Buckwheat Honey ) and some chestnut honey. I find the chestnut honey more interesting, as it comes from Georgia (the country) and someone on Amazon posted the following in the comments: "The Caucasian Bee, to which Georgia is the central homeland, is the bee known for its longest proboscis, enabling it to extract nectar from the deepest nectar tissues, where no other species can. Therefore honey produced by the Caucasian bee is of the utmost quality. This is what prompted me to look for the Georgian honey, and I was happy to discover it on Amazon. This particular honey is from Chestnut tree and has incredible aroma and delicious taste. Once I tried a spoonful of this honey I have start craving for it nonstop. This honey is so good that it will blow your mind." https://www.amazon.com/dp/B07W8FMFCB/ref=cm_sw_em_r_mt_dp_U_gBtPDb151VK5X I am not sure it's true and don't have the time to check now, but it's a great bee story :)
  3. While this thread is about a more complex concoction, let me throw this into the fray: "Metformin is sometimes proposed to be an “anti-aging” drug, based on preclinical experiments with lower-order organisms and numerous retrospective data on beneficial health outcomes for type 2 diabetics. Large prospective, placebo-controlled trials are planned, in pilot stage or running, to find a new use (or indication) for an aging population. As one of the metformin trials has “frailty” as its endpoint, similar to a trial with a plant-derived senolytic, the latter class of novel anti-aging drugs is briefly discussed. Concerns exist not only for vitamin B12 and B6 deficiencies, but also about whether there are adverse effects of metformin on individuals who try to remain healthy by maintaining cardiovascular fitness via exercise. ... In contrast to rapamycin, where data from all preclinical trials on mouse models and other lower-order organisms prove that the drug increases the lifespan (“longevity”), there is little such evidence for metformin (see below). Rapamycin also increases the health span or even reverses age-related diseases (“rejuvenation”) in worms, flies, mice, rats, and dogs. ..." https://www.karger.com/Article/FullText/502257
  4. Yep. Sibiriak beat me to it.
  5. Ron Put

    Saturated fat - a skeptic's view

    It says per g.
  6. Ron Put

    Bottle of Lies

    Life-expectancy has recently fallen for white males in the US, as well. Different interest groups spin these things differently. The most plausible explanation is that the "easy" pickings in improving life expectancy, such as infant mortality, tobacco use and the elimination of major environmental hazards have been largely dealt with in most advanced countries, especially in the middle class segment. There are groups within such societies which are still catching up, but some groups have peaked. At the same time, obesity is still raising among the poor and the middle class, so it's reasonable that some of its effects are starting to chip away at the already peaked numbers. The Guardian article doesn't give demographics, so it's rather uninformative, other than as a click-bait headline and a platform for interest groups to pull the proverbial rug their way. I am certain that there are many issues with generics. I am sure that there are some issues with Big Pharma, too, albeit likely less, due to more robust regulation in their host countries. Those must be dealt with. But "the sky is falling" crowd should calm down -- if there was such a major problem and it was not addressed by the regulatory authorities, there are plenty of firms looking for profitable class action cases in places like the US and the UK, and trust me, we would hear a lot more about it. As is, the panic I sense in some here just helps sell more expensive versions of a given drug, even if such branded versions are sometimes produced in the same facility which produces the maligned generics.
  7. Thanks, Sibriak. As to plant v. animal protein and fat, I found this rather long interview to be a pretty good overview:
  8. I don't necessarily hold Attia in the highest esteem, but the last sentence excerpted by Todd makes the bottom line point, IMO: "After 1-year of treatment, there was “highly significant” evidence of a restoration of thymic functional mass along with improvements in age-related immunological parameters, based on MRI imaging and favorable changes in monocytes and T-cell changes. Insulin levels were reportedly controlled, so as far as preliminary studies go, it’s an intriguing finding, with certainly a lot more to learn."
  9. Ron Put

    Testosterone, Luteinizing Hormone and Mortality

    Low total testosterone and high SHBG are certainly not likely to be optimum for good health, based on what I read, as it would normally mean not enough free T. Ultimately, too little available testosterone correlates with higher mortality, in fact more so than having T which is too high (over 1500). All I was saying was that Saul's high T was balanced out by the high SHBG, while still providing enough T for the functions required for optimum health. The genetic predisposition to high T in the article I cited was more interesting to me.
  10. Hah! While I agree that based on past HGH long term studies, this needs to be replicated in a larger group and safety should be determined over a longer period, before we get too excited. But for what it is (including the financial interests disclosed by some of the researchers), it's actually not a bad study. And it is certainly a bit more rigorous and based on somewhat better methodology than the Luigi CR study discussed in the testosterone thread 🙂
  11. Ron Put

    Testosterone, Luteinizing Hormone and Mortality

    From what I read, free T is normally about 2%-3% in the average adult male (e.g., https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2544367/ ), probably closer to 2%. If total T is toward the bottom of the scale, 1% is on the low side and it can affect one's functions, including muscle-building ability. Of course, the crucial point is, 1% of what? If of 300, then it's certainly too low. But if 1% of 900, then it's good. Which is what the first article I posted seems to imply, and why it reminded me of your (Saul's) case. Do you know your SHBG values? My guess is they would be on the higher side.
  12. Ron Put

    Testosterone, Luteinizing Hormone and Mortality

    Just came across an interesting article suggesting that high SGBH (which implies lower free T) is beneficial. It would seem that high total T combined with high SGBH may be the golden combination -- Saul's high T and 1% free T may be explained by high SGBH. There are appears to be some genetic component: Recent studies have identified that there may be a link between SHBG levels and insulin resistance in type 2 diabetes. It has been suggested that SHBG may have a causal role in the risk of type 2 diabetes since Mendelian randomization studies have reported that carrying specific SHBG single-nucleotide polymorphisms affects the risk of type 2 diabetes 7). Carriers of rs6259 polymorphism were shown to have higher SHBG levels and a lower risk of type 2 diabetes, and rs6257 single-nucleotide polymorphism carriers were reported to have lower SHBG levels and higher risk of type 2 diabetes 😎. In another larger study including 86138 adults, presence of the rs1799941 SNP was associated with increased SHBG concentrations and reduced risk of type 2 diabetes after correction for age, sex, and BMI 9). In a recent study, Wang et al 10) showed that circulating SHBG levels were predictive for future insulin resistance in healthy young Finnish adults, whereas Mendelian randomization suggested minor, if any, causal effects. https://healthjade.net/shbg/
  13. Very interesting. But as we've already witnessed the previous wave of GH hype, I'd say it's probably prudent to see this replicated and longer term studies showing the safety of such supplementation.
  14. Ron Put

    Finally Some Useful Insights about Gut Bacteria and Health

    For those interested, here is a good broad summary of how to interpret one's bioflora test results: "How to interpret your microbiome results? Brown et al. (2011) explained how butyrate-producing bacteria protects your gut from inflammation, ulcerative colitis and colorectal cancer. Six main families of firmicutes are known for their ability to convert lactic acid into butyric acid (butyrate). These are Anaerostipes, Flavonifractor, Faecalibacterium, Pseudobutyrivibrio, Roseburia and Subdoligranulum. Butyric acid induces mucin synthesis and tightens the junctions between epithelial cells, thus preventing inflammation and leaky gut syndrome. Nevertheless, Bacteoridetes like Bacteroides and Alistipes will convert lactic acid into other short-chain fatty acids (SCFAs) like acetic acid, formic acid or propionic acid, which, if present in too large quantities, will damage the lining of the gut, causing inflammation and hyperpermeability of the intestines, leading to autoimmune diseases. So, although Bacteroides and Alistipes are useful and beneficial to digest whole grains and fats, if their proportion exceeds that of the butyrate-producing firmicutes above, it will most probably cause illness. It is therefore important to keep a higher ratio of butyrate-producing bacteria - if possible two or three times more than the Bacteroides and Alistipes. But you also don't want to have too few Bacteroides and Alistipes, as they can also protect you against pathogenic bacteria."
  15. Ron Put

    Saturated fat - a skeptic's view

    According to Comer Lab, Navitas nibs contain about 35.3 mg/g of flavanols and Navitas powder contains about 25.8. But my understanding is that cacao is very nutritionally complex, so I'd be leery of focusing on just one aspect of it.