Jump to content


  • Content Count

  • Joined

  • Last visited

Recent Profile Visitors

The recent visitors block is disabled and is not being shown to other users.

  1. If you eat a lot of whole grains, legumes, and greens, you will get a lot of betaine. Betaine is one of the metabolites of choline used for methylation, so eating it directly contributes to the choline requirement. According to Chris Masterjohn it's good for up to half of the requirement, so you'd only need 275 mg choline.
  2. I think the Adventist Health Studies certainly still have a lot of value. They are prospective cohort studies on actual individuals going to the doctor over many years, not based on demography data. And as for the Okinawans, there are old autopsy studies you can read documenting clear arteries and other signs of health, and other studies that are not this kind of correlational observational epidemiology. Also, I think there is a difference between areas with many supercentenarians, and ones with high average life expectancies for people 80+. Does bad data affect the latter enough to create blue zones out of people who actually weren't especially healthy at all? I'm not sure. Anyway, the Blue Zones org has responded: https://www.bluezones.com/news/are-supercentenarian-claims-based-on-age-exaggeration/ Obviously they have a huge interest in not being invalidated. Hopefully, when the paper comes out, we will get some commentary from epidemiologists with no biases.
  3. Great points everyone. Loma Linda wasn't included in the preprint but the author implied on twitter that it has issues as well: Although, we don't need centenarians to prove that the SDAs involved in AHS had excellent health and lived longer than average.
  4. New biostats preprint: Supercentenarians and the oldest-old are concentrated into regions with no birth certificates and short lifespans Several years ago was this, not sure if it has been discussed before: Japan, Checking on Its Oldest, Finds Many Gone The Japanese pensions scandals (published in the international journal of pensions!) Bit of an overstatement, as we still have prospective epidemiology that generally agrees with the overall principles, but. Does anyone think this casts doubt on accepted blue zone anecdata?