Mike Lustgarten

Kidney function may be an important part of the TMAO story:

Part II of this series: Blood Test #3 in 2022: Supplements, Diet

Resting Heart Rate And Heart Rate Variability: What's Optimal, 4-Year Progress

Blood Test Analysis: Italian Centenarians

I'm not worried about oxalate causing kidney stones, but bone density. Oxalate binds calcium 1:1, so with a higher intake of oxalate than calcium, even on a calcium-sufficient diet (> RDA), I'd bet that there could be issues related to bone density. I haven't come across any published literature for that, unfortunately. But also, most people don't eat 180g of spinach/d, so it's unlikely that data exists. I already get a sufficient amount of nitrates from ~210g of daily beets, and have replaced the spinach with collards, which are low in oxalates yet still high in Vitamin K. We'll see if/how the switch affects my blood biomarkers on upcoming tests.

My average calcium intake is 1200 mg/d, but I've averaged as high as 2000 mg of oxalate/d. When considering that calcium binds 1:1 to oxalate, I wonder how much calcium I would actually absorb with that much oxalate. I'm not worried about kidney stones, but in contrast, bone density. I've since replaced my 5-6 oz of daily spinach with collards, which are low in oxalates.

Unfortunately, Cronometer doesn't include methionine intake for all foods-for example it isn't listed for the brand of sardines or cacao that I commonly eat. That's why I went with total protein instead. I average 85g of fiber/d, so I eat lots of plants and correspondingly, plant protein. If I calculated it, at least 70% of my protein intake is from plants, with the rest from animal sources (fish, yogurt, some parmesan cheese). I use WHOOP, not Garmin... Cronometer recently added oxalate to its measures. It's under "Settings-->Profile and Targets", and then at the bottom of the page you can make oxalate visible.

Do you mean methionine from plants vs animal products?

How Much Oxalate Is Too Much? n=1 Analysis