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Main CALERIE II Results
Michael R posted a topic in CR Science & TheoryAll: This is evidently the main report from the CALERIE study, an NIA trial that was billed as a CR feasibility study in humans. Most earlier "CALERIE" reports came from pilot studies, which unfortunately used entirely overweight and obese people, making it impossible to disentangle beneficial effects or effects suggesting CR's translatability from simple obesity-avoidance effects. CALERIE proper was somewhat more selective — "Body mass index averaged 25.1 (range: 21.9–28.0kg/m2)" — but this unfortunately still leaves a lot of suspect data points. Additionally, the degree of CR intended was mild, and that achieved and sustained was even milder. Anyway, here is the abstract of the CALERIE report: I should be able to get access to the full text soonish, and will provide more details if someone else doesn't beat me to it.