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  1. All: This is the first clinical trial to show that a comprehensive prevention intervention can slow the rate of cognitive decline in the normal elderly. The guidance here is consistent with the epidemiology and generally-accepted health advice, of course, but that's exactly why the trial was structured this way: (a) because you want to try what you think is grounded in evidence, but also ( B) the very fact that everyone is assuming that this is the way to go and that it's being widely recommended makes it all the more important to actually test it.