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"Dr. Aubrey De Grey is a biomedical gerontologist and the Chief Science Officer at SENS Research Foundation, a biomedical charity that funds research dedicated to combating aging. His research interests encompass the characterization of all the accumulating and eventually pathogenic molecular and cellular side-effects of metabolism (“damage”) that constitute mammalian aging, and the design of interventions to repair and/or obviate that damage. In line with his research, De Grey gave a talk at The Aspen Abu Dhabi Ideas Festival focusing on “Rejuvenating Biotechnology: Why age may soon cease to mean aging”."
The longevity Live Chat is growing really fast and more and more people are connecting. Lots of detailed discussions on what is new in anti aging. Conversations about SENS, Aubrey De Grey, and many other initiatives that are getting us closer to the end goal of keeping aging under medical control. The live chat can be found here: https://discord.gg/ftSbffu It's great for us to be connected and work together. I'll keep making youtube videos on Longevity / aging, as well as help introduce people from different lines of work to each other with the end goal of hopefully speeding up the research and development of anti aging therapies. Cheers!
Aubrey remains pretty skeptical of the benefits of CR in humans. http://www.planettechnews.com/interviews/ptn-interviews-dr-aubrey-de-grey-researcher-and-a-thought-leader-in-anti-aging-regenerative-medicine Here is the relevant section from this Q&A article : Q: You comment in your talks that tinkering with metabolism is not a viable approach, because it is too complicated and impossible to modify without causing "more harm than good". However, it seems a number of anti aging companies, focused on drugs and genetic engineering, seem to be pursuing this route. Can you explain this disagreement? Aubrey: Great question. The short answer is that there is one exception to my comment, but it’s an exception that doesn’t seem likely to have much practical significance for humans. The exception is calorie restriction. The drugs and other simple interventions (including genetic ones) that companies are looking at are almost all focused on making the body behave as if it is in a famine. The motivation, of course, is that famine (and these drugs) can greatly postpone aging in short-lived laboratory organisms like mice, rats and (even more so) worms. But it turns out - and for very obvious evolutionary reasons - that this doesn’t work nearly so well in long-lived species as in short-lived ones. The most that I think humans can possibly benefit by that kind of approach is a couple of years.
Michael R posted a topic in ChitchatRB2015 is fast approaching: August 19-21, 2015 at the Hyatt Regency near the San Francisco Airport. The few of you who have been fortunate enough to attend SENS Research Foundation's longer-running SENS Conferences in Cambridge, UK will already know that they're incredibly exciting meetings, highlighting the most important progress in the biotechnologies of rejuvenation, and are always extremely intellectually stimulating, as they bring in a mix of speakers from a wide range of biomedical disciplines. The Rejuvenation Biotechnology (RB) Conference series has equal caliber science, but centers around fostering collaboration to build up a rejuvenation biotechnology industry, bringing together researchers with biotech startups, representatives from the heavy hitters of Pharma, and policymakers to show how the power of Silicon Valley and biotech entrepreneurship can be put to work against age-related disease and disability. (Check out the Rejuvenation Biotechnology Brochure and Agenda — and we are still waiting for final confirmation on a few high-profile speakers). Believe me, for the scientifically-inclined advocate for rejuvenation biotechnology, these are intellectual thrill rides you'll not want to miss! Super Early Bird Registration (with the best discounts) ends June 15th, so sign up soon!