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  1. I recently picked up some Acetyl-L-carnitine (500mg) combined with racemic Alpha Lipoic Acid (150mg), after reading many reports of benefits with energy / memory / mitochondrial function, which seems like a helpful component of an anti-aging strategy. While my body fat % is quite low, I've been eating an ad libitum diet for most of my life, if not a fairly high calorie diet while exercising and lifting weights / gaining muscle. I've been dialing down on my methionine / caloric intake over the past few weeks toward a mild CR diet, and came across this article: Dietary lipoic acid supplementation can mimic or block the effect of dietary restriction on life span: http://www.ncbi.nlm.nih.gov/pubmed/18486188 What are your thoughts on this article? Are there other supplements / foods that nudge genetic expression toward a beneficial CR profile?