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  1. All: Diet quality may play into this, and the fact that the 27.4 ± 2.5 kg/m2 average BMI in the controls includes some significantly overweight people. And it's n-12, and only in the colon, where narrow diet effects might be most strongly observed (note that dietary influences on colorectal and GI cancers are more consistent than other tissues). But it seems pretty good evidence that human CR suppresses SC accumulation rather strongly, consistent with CR's tranlatability.
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