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Found 6 results

  1. https://nutritionfacts.org/video/coconut-water-and-depression/ Here is Dr. Greger's latest video in the world of nutritional science. Don't let the name 'Coconut Water and Depression' mislead you. Watching a video like this is profoundly disturbing on so many levels. Misallocation of research funds, animal abuse, misreporting of research, and much more. Take a look, but first a warning, you may find it disturbing.
  2. UCSFShapeUpStudy

    UCSF Shape Up Study

    Do you live in the San Francisco Bay Area? Are you interested in learning your body fat, muscle and bone status? You may be interested in participating in the Shape Up! Study. We are funded by the National Institutes of Health (NIH), so there is NO cost to you for participating in the study. ALL study procedures will take place at University of California, San Francisco (Parnassus Campus) The goals of the study: Provide phenotype descriptors of health using body shape, derive predictive models of how body shape relates to regional and total body composition and bone mineral density over a wide ranges of ages, BMI, and ethnicity for both sexes. Examine the relationship of optical body composition estimates and metabolic risk factors. If you are between 5-17 years old, you might be eligible for Shape Up! Kids (pdf) If you are between 18-80 years old, you might be eligible for Shape Up! Adults (pdf) Eligibility: able to lay flat on your back for up to 10 minutes able to stand without aid for 2 minutes no metal or artifacts that cannot be removed Benefits: A $50 Amazon gift card Body composition reports (DXA report, MRI (for kids only), whole body 3D scan) Complete blood count report Please email us at bodycompstudies@ucsf.edu or call us at (415) 741-3454 if you are interested in participating. Like us on our Facebook page: https://www.facebook.com/BodyCompositionUCSF/ Check out our Lab website: https://radiology.ucsf.edu/research/labs/breast-bone-density Please let us know if you have any questions or how to get screened for eligibility. Best Regards, The Shape Up Study Team UCSF Body Composition, Exercise Physiology, and Energy Metabolism Laboratory Department of Radiology and Biomedical Imaging Phone: 415-741-3454 Directions | Like us on Facebook Our Lab Website
  3. How the sugar industry sweetened research in its favor By Jacqueline Howard, CNN Updated 12:26 PM ET, Mon September 12, 2016 http://www.cnn.com/2016/09/12/health/sugar-industry-heart-disease-research/index.html Story highlights A new paper claims the sugar industry funded early heart disease research Experts compare the findings to the tobacco industry's controversial history Sugar Association: "It is challenging for us to comment on events that allegedly occurred 60 years ago" Special Communication | September 12, 2016 Sugar Industry and Coronary Heart Disease Research -- A Historical Analysis of Internal Industry Documents FREE ONLINE FIRST Cristin E. Kearns, DDS, MBA1,2; Laura A. Schmidt, PhD, MSW, MPH1,3,4; Stanton A. Glantz, PhD1,5,6,7,8 JAMA Intern Med. Published online September 12, 2016. doi:10.1001/jamainternmed.2016.5394 http://archinte.jamanetwork.com/article.aspx?articleid=2548255 Abstract Early warning signals of the coronary heart disease (CHD) risk of sugar (sucrose) emerged in the 1950s. We examined Sugar Research Foundation (SRF) internal documents, historical reports, and statements relevant to early debates about the dietary causes of CHD and assembled findings chronologically into a narrative case study. The SRF sponsored its first CHD research project in 1965, a literature review published in the New England Journal of Medicine, which singled out fat and cholesterol as the dietary causes of CHD and downplayed evidence that sucrose consumption was also a risk factor. The SRF set the review’s objective, contributed articles for inclusion, and received drafts. The SRF’s funding and role was not disclosed. Together with other recent analyses of sugar industry documents, our findings suggest the industry sponsored a research program in the 1960s and 1970s that successfully cast doubt about the hazards of sucrose while promoting fat as the dietary culprit in CHD. Policymaking committees should consider giving less weight to food industry–funded studies and include mechanistic and animal studies as well as studies appraising the effect of added sugars on multiple CHD biomarkers and disease development.
  4. James Cain

    Weekly research updates

    I'm going to attempt regularly posting a list of relevant CRON research articles published or indexed on PubMed during the previous week. These may or not be accompanied by commentary, but will at least keep a pulse on new and relevant research happenings. The list will fairly short and mostly directly related to CRON. Some considerations: There are many new research articles on general nutrition or some molecular pathways associated with CRON but which don't directly make CRON the focus of the paper, in which case it will not be included here. Please post and discuss these in other threads. Free full-text is not guaranteed to be available. At some point we may set up a thread or subforum for requesting scientific papers from members who have access, or you can directly message another member to request the full-text, but please respect copyright laws and do not post the full-text of articles which are not freely available as such. Feel free to provide commentary or ask questions related the the posted papers!
  5. All, Sthira has several times (e.g. here) plaintively called for the more widespread application of advances in the burgeoning field of artificial intelligence to the problem of defeating aging. You would think Google-owned Calico would be leading the charge in the arena, and perhaps they are. But Calico's inner workings are quite opaque, and judging by the apparent vaporware status of the glucose-monitoring contact lenses supposedly under development at Verily, that other Google-owned, health technology-focused company, we may be waiting a long time for results from Calico... Fortunately, it appears others in the tech industry are picking up the torch of applying AI to the problem of aging. This announcement talks about a partnership between the Life Extension Foundation (LEF) and Insilico Medicine, a Big Data / AI startup that was spun off from Johns Hopkins University that is focused on applying deep learning to drug discovery. According to the press release, the partnership will focus on discovering "effective nutraceuticals that promote the young healthy state in old tissues and support health and longevity." In a bit more detail: Insilico Medicine will focus on applying advanced signaling pathway activation analysis techniques and deep learning algorithms to find nutraceuticals that mimic the tissue-specific transcriptional response of many known interventions and pathways associated with health and longevity. They will also search for dietary ingredients referred to as "geroprotectors" that mimic the young healthy signaling state in older human tissues. Life Extension will use this information to develop novel nutraceutical products to support health and longevity. While I'm not very optimistic about the prospects of dramatic life extension via pharmacological interventions, it's good to see AI, Big Data and deep learning being applied to "advanced signaling pathway activation analysis". It seems to me that any true longevity breakthrough will require this sort of analysis to help unravel the incredible complexity of human metabolism as it relates to aging, whether it can ultimately be translated into "geroprotector" nutraceuticals or (more likely) not. --Dean
  6. Sthira

    On pursuing Biogerontology

    Your thoughts, if, say, hypothetically you were thinking of entering the fray. I copy and paste from: http://www.senescence.info/biogerontology_career.html How to Become a Biogerontologist senescence.info logo Biogerontologists study the biological process of aging at different levels and using different techniques and models. If you would like to do research on the biology of aging and/or you are a student thinking about pursuing a career in biogerontology then this brief essay is for you. Keywords: age-related diseases, gerontology, gerontologists, jobs By and large, biogerontologists work at research institutions, typically universities and laboratories, though some also work in the biotechnology industry--and a few companies research aging. The vast majority of biogerontologists have a PhD (or sometimes an MD or both), so if you want to become a biogerontologist you should be prepared to go to graduate and/or medical school. While it is possible to study aging in a private company or as a staff member of a research institution, the majority of influential biogerontologists have their own research group, like mine, at a research institution. Again, you can certainly contribute to research on aging in a variety of ways and even without making of it your main job, yet if you are serious about becoming a biogerontologist and doing independent research at the highest level then this usually implies developing an academic career. If you have an entrepreneurial spirit you could create, or help build up, a biotech company with some focus on aging. You could then do research, usually with translation to humans as a shorter-term aim than in academia, that has commercial value. Although there are a few people working on aging who followed this path, they are a minority and I know very little about entrepreneurship so cannot offer much advice on this--but wish you good luck. As such, this essay focuses on academia. How to develop a career in science is the subject of another essay of mine. Briefly, an academic career is highly competitive and usually entails having good grades in high school (in particular in science classes), getting a bachelor's degree with honors and later a doctoral degree (and maybe a master's degree in between, though I normally do not recommend it as top students can often enter a doctoral program without a masters), obtaining strong recommendation letters from advisors, and eventually developing a publication record, securing grants, and doing some teaching. If you are a student, you should have a counselor at your institution that can guide you through the process and there are also many resources on pursuing an academic career on the Internet. One major doubt of students is which topics they should study to prepare themselves for a career in biogerontology. Because aging is a biological process I would suggest that you include biology courses in your education. With the sequencing of the human genome and recent progress in the genetics of aging and longevity, I would also recommend some knowledge of genetics. Nevertheless, do not overestimate the importance of choosing the right courses and university. It does not make such a big difference because many different techniques and skills can be employed to study aging. There are physicists, physicians, engineers, biologists, geneticists, computer scientists, mathematicians, and many other different professionals studying aging right now. Therefore, my advice is for you to learn different skills, understand the science of aging, and focus on the area you find more exciting or more adequate to your personal situation. (As a side note, I would also recommend you develop good communication skills, both written and oral, as these are crucial not only in academia but in many other careers as well.) In the end, remember that who you are is more important than what you learn. To quote Einstein: "Creativity is more important than knowledge." Even though my opinion might be biased, I definitely think my essays on the biology of aging are an excellent introduction to anyone wishing to pursue a career in biogerontology. A briefer overview of gerontology is available as one of my papers (de Magalhaes, 2011). Nonetheless, I also suggest you take a look at my book recommendations since there may be other sources that better fit your personal taste. Lastly, there are occasional intensive courses on the biology of aging, such as the Molecular Biology of Aging course in Woods Hole, MA, USA. As an undergraduate, I would recommend you gain some research experience. This might also help you decide whether doing research is the career for you. For example, you can do an internship in a research group, like ours, and often your mentor or counselor will help you arrange this. I should note that I am always glad to help students aspiring to develop a career in aging research so if you wish to visit our lab or even spend some time here to see what we do just let me know. Once you become more familiar with research in general you will need to start reading academic papers. The main bibliographical database in the biomedical sciences is PubMed and you will need to become familiar with it at some point in your career, possibly in high school or the latest in college. At some point before going to graduate school, I would advise students to start identifying those researchers in the field whose work they most admire and sub-fields of particular interest. This can be done through publications, though often it is difficult for beginners to make sense of the massive archive of publications. Therefore, I would also advise you to look at the list I maintain of researchers working on aging, which includes links to the researchers' websites (if available) and links to PubMed that allow you to more quickly find relevant publications by each of the researchers. Similar to the point made above about how there is no right topic to study, there is no right school or even degree. Assuming your priority is research on aging then having a PhD has advantages over having an MD since it is difficult to balance research and clinical work, but more often than not this is a personal choice and many people enjoy clinical work. Regarding the choice of countries, this is certainly influenced by the mobility of each individual but a few points may be worth considering. The US and European systems are different in regard to graduate and medical schools. For example, graduate students in the US usually take longer to receive their PhDs. Mostly because of this, and please have in mind that I am an European, I normally would not recommend for an European to get his/her PhD in the US, but like many other suggestions in this essay this is often a personal decision. It is also possible to get a PhD from an European institution but do part or even most of the work in the US. Likewise, many people carry out most of their doctoral work in Europe or in the US but then receive their PhDs from institutions in other countries, often their native countries. Overall, working on aging has its challenges, such as the lack of adequate models of human aging and a lack of funding when compared to other biomedical disciplines. Salary-wise, in fact, working in academia is not the best career choice. Scientists usually do research because they love it, not because they want to become millionaires, though some scientists are also associated with industry which brings in extra income. Working in academia does have its advantages, such as schedule flexibility and creative freedom. Besides, since the field of aging is still largely mysterious with many unanswered questions, bright young minds have an extraordinary opportunity to make important contributions to science by studying aging. I hope you will be one of those minds. Please feel free to contact me if you have questions not covered in this essay or need any advice. Up to the Visitor's Resources Back to senescence.info Thank you for visiting my website. Please feel free to contact me if you have any questions, ideas, comments or suggestions. Copyright © 2007, 2008, 2012 by João Pedro de Magalhães. All rights reserved.
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