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drewab posted a topic in CR Science & TheoryAll, I was wondering if CR has ever been studied in large creatures? It seems that the effects of CR seem to scale down as the size of species goes up. For example, I believe we can double or triple the lifespan of flies and worms, and modestly extend maximum lifespan in larger species like dogs. The evidence for humans is of course murky and the jury is still out on whether maximum lifespan will be effected, or just health span. I'm wondering though if CR has ever been studied in a species physically larger than humans. Perhaps horses? Deer? Cows? Buffalo?