Todd Allen Posted May 1, 2018 Report Share Posted May 1, 2018 As hepatic glycogen depletes muscle becomes very insulin resistant to spare glucose for the brain. It typically takes about 3 days after glycogen repletion before insulin sensitivity is restored. Typically insulin sensitivity will be better than it was prior, probably due to a reduction in hepatic and intramuscular lipids. Thanks Todd for the explanation, it sounds reasonable Have you checked your blood sugar recently? It ought to be better now. My varied fasting practices along with staying lightly in ketosis when not fasting has brought my blood sugar down from roughly 120 mg/dl 2 years ago to now typically being 65-75 mg/dl, which is my target range. The amount of carbohydrate I can consume and stay in that range is increasing slowly suggesting continuing improvement of insulin sensitivity, probably in adipose but maybe muscle too. And this has happened while increasingly shifting to a diet heavy in things believed by many to be metabolically risky such as eating a lot of fat including saturated fat, red meat and pork, eggs - currently 2 dozen+ weekly, high salt and heavy niacin use. Every other tracked biomarker of health has improved except for LDL cholesterol which was previously mildly above the reference range but has since increased by 50%. That prompted a better particle count test which came back solidly pattern A and an evaluation of being categorized lowest risk. High LDL is considered a clinical feature of my neuromuscular disease although as far as I know there has been no investigation of it. Curiously in some other neurological and neuromuscular diseases high cholesterol correlates with better outcomes. Quote Link to comment Share on other sites More sharing options...
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