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drewab

Sleep thought of the day

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There are many factors, which act as stressors on the body, and seem to contribute to improved health outcomes. Some of these include:

  • Exercise
  • Fasting
  • Cold exposure
  • Caloric restriction
  • Heat exposure 
  • Particular foods that exert hormetic effects (ie. cruciferous vegetables)

Some of the above are not without their controversies, but it's interesting that mild sleep deprivation (a mild stressor) doesn't elicit a hormetic effect. Or perhaps it does?

 

Has anyone else had this curious thought before and unpacked it a little?

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I was always thinking that if prolonged sitting is very detrimental to cardiovascular system, then what happens when are sleeping? Sleeping is a period of minimal movement of the body, and by a very simple logic we should interrupt our sleep couple of times during the night, right?

 

Is there any study that investigates this issue, i.e. by comparing especially for CV health, people who interrupt their sleeps during the night (stands up for physiological needs not for psychological reason) between people who sleep in one shot?

Edited by Burak

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I was always thinking that if prolonged sitting is very detrimental to cardiovascular system, then what happens when are sleeping? Sleeping is a period of minimal movement of the body, and by a very simple logic we should interrupt our sleep couple of times during the night, right?

 

Is there any study that investigates this issue, i.e. by comparing especially for CV health, people who interrupt their sleeps during the night (stands up for physiological needs not for psychological reason) between people who sleep in one shot?

 

here are some studies recently cited by Luigi fontana on the importance of a good sleep, I haven't read them, but maybe are interesting:

 

1)Sleep drives metabolite clearance from the adult brain.

https://www.ncbi.nlm.nih.gov/pubmed/24136970

 

2)

Sick and tired: Does sleep have a vital role in the immune system?

http://www.nature.com/nri/journal/v4/n6/full/nri1369.html

 

3)

Sleep promotes branch-specific formation of dendritic spines after learning.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447313/

 

4) And on the converse: 

Sleep, circadian rhythms, and the pathogenesis of Alzheimer disease.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351409/

 

 

 

Sorry for the bad format, but here is night, I have still to finish some work before going to bed,... t0o late :-)

Edited by Cloud

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I used to average about 6 hours of sleep per night (and intermittent bouts of severe insomnia) when I was suffering rapid deterioration with my neuro-muscular wastiing disease.  I've made numerous changes since then but one I think has been highly beneficial is getting much more sleep and many of my changes have been in support of the goal of better sleep.  I'm now almost always asleep within a few minutes of lying down and typically sleep 9 hours per night.  It seems that most of my exercise recovery, muscle repair and growth occurs while sleeping.  I needed more sleep to be able to push myself harder and the exercising is now making me sleep deeper and longer.   I'd sleep longer if I could figure out how, but once I'm awake I don't find benefit from additional time lying in bed and tend to get up about as quick as I go to bed.

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I have a question about hormesis. It is a concept proposed by Mattson and we think that it is one of the cause of benefits of  Exercise, Fasting,Cold exposure, Caloric restriction, etc.

But I wonder how much it has been verified experimentally, like for example the autophagy, it could be that hormesis is a very nice principle but nevertheless not explaining everything.... what do you think?

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I know wikipedia is not a 100% reliable source but the page on hormesis sounds reasonable to me.

https://en.wikipedia.org/wiki/Hormesis

 

My take from that page is that hormesis is a soundly established concept with many examples showing solid evidence of the principle but there are also cases where it is hypothesized to be a factor (wouldn't it be great if a little radiation or pesticides were good for you!) but there is little or no supporting evidence. 

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