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mikeccolella

Fish oil associated with longer telomeres

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Im currently reading “ The Telomere Effect” by nobel prize winner Elizabeth Blackburn. She cites a study that measured telomere length and showed that of three groups the ones taking the most fish oil ended up with the longest telomeres. Long Telomeres are strongly associated with longevity.

 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545053/#!po=42.6471

 

What is noteworthy is that the fish oil improved the ratio of omega 3 and omega 6 and this was cited as the probable factor based on the physiological effects of lowering this ratio. If that is correct then it may not be specifically fish oil but merely the effect this had on lowering the ratio

Edited by mikeccolella

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Long Telomeres are strongly associated with longevity. 

 

In what way "associated"? I've seen studies showing longer telomeres leading to longer lifespans as well as shorter lifespans, more cancer, etc. - at the cellular level and so on. I'm interested when it shows a clear correlation (1) in humans and (2) lifespan, all cause mortality impact.

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Shorter telomeres in a2015 copenhagen study of 64,000 people showed that the shorter your telomeres the earlier you die from cancer, cardiovascular and simply dying at younger ages in general. People with the longest telomeres were the healthiest and short telomeres were associated with sickness. The kaiser permanente study of over 100,000 people measured telomere length and three years later it showed people with shorter telomeres were more likely to die . The study controlled for factors like race, drinking, bmi, physical activity etc.etc. The health abc study showed longer telomeres = more years of healthy life and the authors cite meta analysis reviews that reach the same conclusions. The authors of the book conclude that the science is very strong in favor of the telomere effect on our health and longevity and that long telomeres are strongly associated with vigor and longevity. Of course with anything excess can lead to problems and they do mention that telomerase enhancers that some are consuming are dangerous and can have bad consequences for health unlike the natural enhancers like our fatty acid ratios, physical exercise, waist hip ratios, sleep and stress.

Edited by mikeccolella

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mikecolella:  She cites a study that measured telomere length and showed that of three groups the ones taking the most fish oil ended up with the longest telomeres.

 

It should be noted that the participants in that study were markedly sedentary and overweight/obese.

 

There were no baseline group differences on SAD or BMI (p > 0.60 for both). Using BMI cut points of 25 and 30 kg/m2, 100 participants (94%) were overweight, and 54 (51%) were obese.

 

Individuals were excluded if they typically engaged in 2 or more hours of vigorous physical activity per week or had a body mass index (BMI) below 22.5 or over 40.

 

Table 1

Baseline characteristics of study population, by intervention group

 

* * *

Body mass index, mean (SD), kg/m2        31.1 (4.8)          31.7 (4.5)       30.7 (3.8)

Edited by Sibiriak

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