kpfleger Posted October 11, 2019 Report Share Posted October 11, 2019 I made a website to track all aging/longevity companies, in an interactive (sortable, etc.) and quantitative way: agingbiotech.info The aging/longevity field has grown to where it's hard to follow. There are books, journals, blog, some industry reports, and a few website with forums like this one, but few structured info sources for broad context or targeted queries, particularly few focused on aging defined as the underlying molecular causes of multiple age-related diseases. The web had no comprehensive & precise list of companies with therapies or diagnostics for underlying aging in this sense. Hope this is helpful to some. For those here, it's particularly worth noting that many interventions being pursued within the aging/longevity communities (both in academic labs and companies) are focused on correcting or making up for age-accelerating factors, either genetic disorders that accelerate some aspect of aging or lifestyle factors that do so such as bad diet, lack of exercise, etc. including their downstream manifestations such as obesity. There is even a new buzz-phrase that succinctly describes a subpart of the field focused on these kinds of things: metabesity (with a conference this month in the DC area even). Interventions that are best categorized into this bucket include category buzz-phrases like CR-mimetics, exercise-mimetics, Rapalogs, etc. Metformin probably goes in this bucket. For those on a CR diet, or even just eating high micro-nutrient, obesity-avoiding, relatively healthy diet (much healthier than average Westerner), there is a question about how much such interventions will do to improve health & healthspan. The website includes companies working on such interventions, but also many working on things that should be important even to those on CR or living close to optimal long-term-health preserving lifestyles. Figuring out the exact boundary of that split is debatable and will only be answered definitively with further science so until then you have to decide which companies and which of their clinical trials are more worth paying attention to than others. But there is certainly important work being tracked. Hopefully this site is a useful way to check out the current state every now and then. Feedback welcomed (see contact link at the site). Karl Quote Link to comment Share on other sites More sharing options...
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