Antioxidants - pathogenic for the heart, in excess

[TomBAvoider]

The antioxident craze has been going on for decades, and despite a lot of pushback over the years, you still constantly read about a diet or food that's healthy because of "antioxidants", not to mention supplements. Perhaps the tide will slowly start to turn, when the idea of harm in excess antioxidants takes hold:

Surplus Antioxidants Are Pathogenic For Hearts And Skeletal Muscle

[drewab]

It would be interesting to see the difference in supplements vs. anti-oxidants in diet and how that could affect outcomes. I'm inclined to believe that anti-oxidants found in the full matrix of food don't pose a problem, and in general, I specifically seek high-antioxidant foods. For example, I generally chose berries over bananas, sweet potatoes over potatoes, dark leafy greens over iceberg lettuce, and so forth. I'm sure that this means that my anti-oxidant intake is higher as a result and believes this will lead to modestly more positive outcomes. 

[mccoy]

We hinted at this topic in other threads. An excess of antioxidants (from supplements, probably not from natural foods) may interfere with the natural ROS signaling, which is a natural metabolic process. By googling  ROS + Navdeep Chandler, I found my own thread in this forum. The neatest thing is that by pasting the URL I paste the post image as well. This platform is excellent. congratulations to the administrators who chose it!

 

 

[TomBAvoider]

I listened to this episode when it came out. In general, I find the Attia medical-related podcasts very interesting, and listen to them when I jog (the other podcasts he has about "leadership" and the like, I skip).

Re: antioxidants from supplements vs food - well, we all know the danger from supplements, but I read once that you can overdo things with food too, I wish I could locate the paper - apparently there is such a thing as too many polyphenols from food - so I'm not sure we're off the hook here when it comes to food. And folks on this board are the very ones who might be candidates for "too many polyphenols or antioxidants from food". 

[TomBAvoider]

This is not the paper I'm thinking about, but here's one:

Risks and safety of polyphenol consumption

 

[mccoy]

The above article cites Paracelsus, who expresses in another words the hormetic principle (all substances are poisons, it's the dose which makes them poisonous).

Same goes for the healthy (in low dosages) polyphenols, which of course can become toxic in higher dosages. Tannin is an example, raw oak corns would kill us, as much as the saponins of raw beans can kill people.

[Ron Put]

Hm, wondering what amount of sulforaphane was used and how it translates to humans.

I am still eating my broccoli sprouts, however.