Jump to content

Methylene blue


Recommended Posts

  • 2 years later...
Quote

 

Methods

The redox agent methylene blue and the cell-permeable succinate prodrug NV118 were evaluated by measuring mitochondrial respiration and lactate production of human platelets exposed to metformin and co-treated with either of the two pharmacological bypass agents.

Results

The cell-permeable succinate prodrug NV118 increased mitochondrial respiration which was linked to phosphorylation by the ATP-synthase and alleviated the increase in lactate production induced by toxic doses of metformin. The redox agent methylene blue, in contrast, failed to mitigate the metformin-induced changes in mitochondrial respiration and lactate generation.

 

 

Link to comment
Share on other sites

  • 6 months later...

imho, the fact of existence of things like this https://www.amazon.com/Ultimate-Guide-Methylene-Blue-Mitochondrial/dp/177723963X should be a kind of a warning

a quick search reveals that the substance was widely used for many decades for research support purposes, thus if there could be some strange effect easily reachable without a special delivery vehicle I would expect already more impressing results and studies, otherwise it looks like no one noticed something promising

but off course I could be wrong with it, for the same probabilistic reasons..

Link to comment
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...
×
×
  • Create New...