corybroo Posted June 4, 2020 Report Share Posted June 4, 2020 MedicalXpress has an article Eat less and live a long healthy life? Study shows 'not in all cases' It challenges the idea that CR will extend both lifespan and healthspan based on a study of 160 genetically distinct strains of fruit fly D. melanogaster. They measured nutrient-dependent changes in lifespan and age-related changes in activity for healthspan. 97 percent of strains showed some lifespan or healthspan extension in response to dietary restriction, only 50 percent of strains showed a significantly positive response to dietary restriction for both. 13% were more vigorous but died sooner; 5% lived longer but with more time in poor health; and 32% showed no benefit or detriment . They identified a gene that when inhibited extends lifespan without changing health span. They found a second gene that when inhibited delays age related decline in physical activity with at best minimal change to lifespan. This is a study of fruit flys not humans and only climbing ability was used to assess physical ability. Quote Link to comment Share on other sites More sharing options...
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