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Age-related impairments reversed in animal model


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I saw this article today:  Age-related impairments reversed in animal model    verifies effect of inflamation on debilitation in aging and explores reversing that.

 

has now demonstrated that visceral adipose tissue, known as belly fat, crucially contributes to the development of chronic low-grade inflammation. 

In a next step, the researchers investigated the possibility to reverse age-related impairments by restoring the immune cell balance in visceral adipose tissue. "In different experimental approaches, we were able to show that transfers of eosinophils from young mice into aged recipients resolved not only local but also systemic low-grade inflammation," 

This approach had a rejuvenating effect on the aged organism. As a consequence, aged animals showed significant improvements in physical fitness as assessed by endurance and grip strength tests. Moreover, the therapy had a rejuvenating effect on the immune system manifesting in improved vaccination responses of aged mice.

 

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5 hours ago, corybroo said:

I saw this article today:  Age-related impairments reversed in animal model    verifies effect of inflamation on debilitation in aging and explores reversing that.

 

has now demonstrated that visceral adipose tissue, known as belly fat, crucially contributes to the development of chronic low-grade inflammation. 

In a next step, the researchers investigated the possibility to reverse age-related impairments by restoring the immune cell balance in visceral adipose tissue. "In different experimental approaches, we were able to show that transfers of eosinophils from young mice into aged recipients resolved not only local but also systemic low-grade inflammation," 

This approach had a rejuvenating effect on the aged organism. As a consequence, aged animals showed significant improvements in physical fitness as assessed by endurance and grip strength tests. Moreover, the therapy had a rejuvenating effect on the immune system manifesting in improved vaccination responses of aged mice.

 

 Good find corybroo! Luigi  Fontana emphasizes waist/height ratio as an important factor in aging. This adds more credence to his position.

Edited by Mike41
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waist/hip, not waist/height.  BMI is useful only in studying groups of people; it is a crude approximation for "amount of visceral fat".  It's simply easier to measure.

The really important factor is whether or not you have a flat belly (low visceral fat); height is not very relevant for individuals. 

  --  Saul

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