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If post-mitotic tissue ages more slowly at the genetic/epigenetic level, then does it also age more slowly (or more quickly) at the proteomic level?


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I swear Vadim Gladyshev did a presentation on measuring differing aging rates between tissues (in terms of metabolomic diversity) and I think he showed that more rapidly dividing cells age faster/accumulate more "strange" metabolites, but the ones that divide more slowly should presumably accumulate more protein aggregates/lipofuscin that can't be diluted too?

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