Ron Put Posted June 3, 2022 Author Report Share Posted June 3, 2022 AI is here, and it's taking over 😉 Quote Link to comment Share on other sites More sharing options...
IgorF Posted September 24, 2022 Report Share Posted September 24, 2022 Jack Szostak, nice set on rna world, pre-modern cells and so on: https://www.youtube.com/watch?v=PqPGOhXoprUhttps://www.youtube.com/watch?v=CJ5jh33OiOAhttps://www.youtube.com/watch?v=jfq5-i8xoIU Quote Link to comment Share on other sites More sharing options...
Ron Put Posted October 9, 2022 Author Report Share Posted October 9, 2022 I found this interesting, DNA does help us understand our origins a bit better. Maybe Covid killed off the Neanderthals 😄 Quote Link to comment Share on other sites More sharing options...
drewab Posted October 23, 2022 Report Share Posted October 23, 2022 An unbelievably good podcast that I think nearly everyone here would enjoy. Quote Link to comment Share on other sites More sharing options...
Ron Put Posted March 27, 2023 Author Report Share Posted March 27, 2023 Quote Link to comment Share on other sites More sharing options...
Ron Put Posted April 8, 2023 Author Report Share Posted April 8, 2023 Quote Link to comment Share on other sites More sharing options...
AlanPater Posted April 8, 2023 Report Share Posted April 8, 2023 13 hours ago, Ron Put said: Quote Link to comment Share on other sites More sharing options...
AlanPater Posted April 8, 2023 Report Share Posted April 8, 2023 True to form, Ron. https://rationalwiki.org/wiki/Richard_Haier Quote Link to comment Share on other sites More sharing options...
Ron Put Posted April 13, 2023 Author Report Share Posted April 13, 2023 (edited) On 4/9/2023 at 1:07 AM, AlanPater said: True to form, Ron. Do you have a rational comment, or any con or pro argument on the merit, or anything thoughtful to say? If you do, I'd be thrilled to read it, perhaps in its own thread. But silly ad hominem attacks against anyone that is at odds with your seemingly strong and rather rigid biases, are uncalled for. Edited April 13, 2023 by Ron Put Quote Link to comment Share on other sites More sharing options...
Ron Put Posted April 13, 2023 Author Report Share Posted April 13, 2023 Quote Link to comment Share on other sites More sharing options...
Ron Put Posted April 16, 2023 Author Report Share Posted April 16, 2023 Quote Link to comment Share on other sites More sharing options...
IgorF Posted June 29, 2023 Report Share Posted June 29, 2023 Herman Pontzer - Evolution Activity and Aging in Human Energy Expenditure An interesting researcher. He recently summarized his vision in a nice pop-sci book "Burn. The Misunderstood Science of Metabolism". AFAIR his research with Hadza+ was used as one of the sources of inspiration by authors of other nice recently published pop-sci books: "Exercised: Why Something We Never Evolved to Do Is Healthy and Rewarding" by Daniel Lieberman and "Ultra-Processed People: Why We Can't Stop Eating Food That Isn't Food" by Chris van Tulleken I personally liked all this stuff, maybe because it resonates well with my own observations, intuition and so on. Br, Igor Quote Link to comment Share on other sites More sharing options...
drewab Posted August 14, 2023 Report Share Posted August 14, 2023 It seems like episodes from Simon Hill's podcast "The Proof," seem to come up regularly on this forum these days. This is a great conversation with Dr. Joel Fuhrman that I am sure many people here will enjoy. Quote Link to comment Share on other sites More sharing options...
mccoy Posted August 20, 2023 Report Share Posted August 20, 2023 I have listened to that. Very interesting episode. I too was a follower of Dr. Sheldon's proposals when younger but in my case, they have been detrimental, since I applied them in too an extreme fashion, with excessive caloric restriction and not optimizing nutrients. As a result, I got sick and to date, I hate to lose weight, remembering the bad health conditions when I reached a BMI of 17.0. Dr. Fuhrman with time has refined his suggestions and I find them sensible as a whole, even not adhering to a vegan regimen. I find that animal protein has the advantage of being effective in a low and digestible amount, whereas plant protein tends to be less effective in low amounts and little digestible in higher amounts. Just my personal experience. Also, nuts protein maybe is not all digested, following the fate of fat (I'm pasting an article on that below). I may follow Fuhrman's suggestion to take moderate amounts (about 250-500 mg) of Omega-3s, far less than usually suggested, his approach may be the winning one. I tend to appreciate moderation unless other approaches are shown to be accurate. In the present controversy about the usefulness of omega3s, this appears a good compromise. Very interesting the part about IGF1, which I'll have to read again. Apparently, regular resistance exercise uses up circulating IGF1, also creating some of it in an autocrine fashion. Energy extraction from nuts: walnuts, almonds and pistachios B. M. McArthur1,* and R. D. Mattes2 Author information Article notes Copyright and License information PMC Disclaimer Go to: Abstract The bioaccessibility of fat has implications for satiety and postprandial lipidaemia. The prevailing view holds that the integrity of plant cell wall structure is the primary determinant of energy and nutrient extraction from plant cells as they pass through the gastrointestinal (GI) tract. However, comparisons across nuts (walnuts, almonds and pistachios) with varying physical properties do not support this view. In the present study, masticated samples of three nuts from healthy adults were exposed to a static model of gastric digestion followed by simulated intestinal digestion. Primary outcomes were particle size and lipid release at each phase of digestion. Walnuts produced a significantly larger particle size post-mastication compared with almonds. Under gastric and intestinal conditions, the particle size was larger for walnuts compared with pistachios and almonds (P < 0·05). However, the masticated and digesta particle sizes were not related to the integrity of cell walls or lipid release. The total lipid release was comparable between nuts after the in vitro intestinal phase (P > 0·05). Microstructural examination showed ruptured and fissured cell walls that would allow digestion of cellular contents, and this may be governed by internal cellular properties such as oil body state. Furthermore, the cell walls of walnuts tend to rupture rather than separate and as walnut tissue passes through the GI tract, lipids tend to coalesce reducing digestion efficiency. Quote Link to comment Share on other sites More sharing options...
Ron Put Posted September 2, 2023 Author Report Share Posted September 2, 2023 Quote Link to comment Share on other sites More sharing options...
Ron Put Posted September 7, 2023 Author Report Share Posted September 7, 2023 A great, simple explanation of the process of autophagy: Quote Link to comment Share on other sites More sharing options...
IgorF Posted September 8, 2023 Report Share Posted September 8, 2023 mouth arcs changes with environment change and far going consequences, interviews with authors of the book Jaws: The Story of a Hidden Epidemic by Sandra Kahn, Paul R. Erhlich https://www.youtube.com/watch?v=tEsbG43lXdE https://www.youtube.com/watch?v=GTZOi2KXU04 (since I am single and have nobody to ask if I am snoring I decided to buy a used continuous pulse oxymeter to see the saturation during the whole night, no idea how good these toys for home users are, better tools have several hundreds - few thousands price and I am not curious enough for them) Quote Link to comment Share on other sites More sharing options...
Ron Put Posted September 30, 2023 Author Report Share Posted September 30, 2023 Quote Link to comment Share on other sites More sharing options...
drewab Posted November 11, 2023 Report Share Posted November 11, 2023 This is an incredible episode with Dr. Rhona Patrick who is well-known for her Found My Fitness Podcast titled "How Vitamin D, Omega 3's, and Exercise May Increase Longevity." It includes an intriguing discussion around vitamin D, magnesium, omega-3 fatty acids, as well as exercise, hormetic stressors, the brain, and inflammation. It was recorded for The Institute of Functional Medicine. The the studies are overlaid with the information she provides makes it a highly engaging and educational video. Quote Link to comment Share on other sites More sharing options...
IgorF Posted November 12, 2023 Report Share Posted November 12, 2023 (edited) I wish we would sometime be able to revive them EDITED TO ADD: critics regarding too wide hypothesizing done by original discovery authors Edited November 14, 2023 by IgorF critics added Quote Link to comment Share on other sites More sharing options...
Ron Put Posted January 4 Author Report Share Posted January 4 (edited) On 11/12/2023 at 10:50 AM, IgorF said: critics regarding too wide hypothesizing done by original discovery authors Thanks. While there are definitely questions about the way this is being presented and interpreted and the second video makes some great points, it always surprises me how convinced humans are of their own absolute uniqueness. Other animals appear to have death rituals (I have witnessed bluejays' behavior that indicated just such a ritual). I may be imagining things in that specific instance, but it is unlikely, IMO, that humans are removed from other animals by a sharp bright line, or that we are the only species to have noticed death or time. Edited January 5 by Ron Put Quote Link to comment Share on other sites More sharing options...
Ron Put Posted January 13 Author Report Share Posted January 13 Quote Link to comment Share on other sites More sharing options...
Ron Put Posted February 18 Author Report Share Posted February 18 Quote Link to comment Share on other sites More sharing options...
IgorF Posted March 1 Report Share Posted March 1 I had no idea where to place it so adding here, S. Jay Olshansky (now doing something for pepsico - a bit of surprise for me) tells that Roy Walford in a private discussion told he doesnt' really believe about possibility of dieting to 120yo at 15:02 approx. I have no judgmenets on the topic, just find it worse to be shared. Br, Igor Quote Link to comment Share on other sites More sharing options...
drewab Posted March 9 Report Share Posted March 9 Quote Link to comment Share on other sites More sharing options...
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