Mike Lustgarten Posted May 30, 2021 Report Share Posted May 30, 2021 Quote Link to comment Share on other sites More sharing options...
Alex K Chen Posted June 2, 2021 Report Share Posted June 2, 2021 (edited) so does starvation reduce fgf21? obese animals have loads of it and are often resistant also it seems like you need fat reserves for this to have tissue to work on? Edited June 2, 2021 by InquilineKea Quote Link to comment Share on other sites More sharing options...
Mike Lustgarten Posted June 2, 2021 Author Report Share Posted June 2, 2021 Why would you expect to need fat reserves for the FGF21 effect? In the FGF21 TG mice, body composition wasn't different when compared with WT (see Fig 1):https://elifesciences.org/articles/00065 Quote Link to comment Share on other sites More sharing options...
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