KHashmi317 Posted September 22, 2021 Report Share Posted September 22, 2021 ... the "axe" being senolytics ... The Sheekey Science Show YT channel posted this video a little over a year ago ... Quote Senescent cells accumulate with age. Studies have shown that removing senescent cells can alleviate symptoms of aging. However, a recent study has put this into question... References; Grosse et al., Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan, Cell Metabolism (2020), https://doi.org/10.1016/j.cmet.2020.0... Xu, M., Pirtskhalava, T., Farr, J.N. et al. Senolytics improve physical function and increase lifespan in old age. Nat Med 24, 1246–1256 (2018). https://doi.org/10.1038/s41591-018-00... Baker, D., Wijshake, T., Tchkonia, T. et al. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature 479, 232–236 (2011). https://doi.org/10.1038/nature10600 Quote Link to comment Share on other sites More sharing options...
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