Jump to content

Reversed Aging in Mice

Recommended Posts

I’m not able to read the entire paper on Nature, but they don’t discuss lifespan.

They do say that the yamanaka factors applied in-vivo were able to reverse epigenetic clocks in skin and kidney.

Reading the abstract the author’s describe true age reversal- assuming that epigenetic clocks are a true reflection of age.

Link to comment
Share on other sites

The mice lived 30% longer:

"Encouraged by this result, the team used the same short reprogramming method during cyclic periods in live mice with progeria. The results were striking: Compared to untreated mice, the reprogrammed mice looked younger; their cardiovascular and other organ function improved and—most surprising of all—they lived 30 percent longer, yet did not develop cancer. On a cellular level, the animals showed the recovery of molecular aging hallmarks that are affected not only in progeria, but also in normal aging."


Link to comment
Share on other sites

So using the same Yamanaka factors - but only 3 of the 4 (or 5); Sinclair explains it once again here, AND he says that THEY ARE TRYING THIS RIGHT NOW in non-human primate trials.

This is the real deal - instructing all tissues that they are a different age.

Biotracking, Age Reversal & Other Advanced Health Technologies (lifespanpodcast.com)

Any issues using this link??







Link to comment
Share on other sites

  • 7 months later...

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.

Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

  • Create New...