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Supplemental estrogens? (eg 17-alpha-estradiol but also the others)


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They may be protective on high oxidative stress seen in autism (but really, they are neuroprotective *in general*) and it would do so much to reduce the gender lifespan gap

17-beta-estradiol is easier to get as a prescription and you can occasionally take them and stop upon the first sign of breast-growth (I have done this several times)

Greg Timblin (https://thesaijolab.org/lab-members) also studies estrogens, though he studies the ROS-hormesis-inducing ones and maybe not the kind we're looking for the most.

Edited by InquilineKea
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Inquiline, if you talk about autism, that's an exceedingly complex subject. For example, some antipsychotics  taken by autistic individuals like risperidone increase the prolactin blood levels, inhibiting testosterone. Now what would be the effect adding another testosterone inhibitor?

It is true that estrogen may be beneficial by testosterone inhibition, it is known that hi levels of T has often an over-activating effect on the brain of autistic adolescente (well, it has such an effect on non-autistic individuals as well).

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  • 1 month later...
On 4/9/2023 at 12:05 AM, InquilineKea said:

you can occasionally take them and stop upon the first sign of breast-growth (I have done this several times)

What do you have against breasts?  I think you should see how long you can take it for and share your longevity data for the greater good!

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Dont we all already get more than we want like this book describes?

https://www.amazon.com/Estrogeneration-Estrogenics-Making-Sick-Infertile/dp/1946546011

I don't think it is so big problem as the book introduces but for a few percents of people it probably makes a real harm.

W/o a strong reason I would not like to mess with hormonal networks, unless a chance for having something bad will be less than 20% and  there is a strong evidence for something really beneficial

Br,

Igor

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