Calorie Restriction Research Moves forward!
The CR Society International is the leader of calorie restriction research in humans. The CR Society Research projects are the first and remain the only longitudinal study of long-term human CR practice. To discuss a human calorie restriction research project, please contact: email@example.com
The first CR Society Research study launched in 2002, with Doctors Luigi Fontana and John Holloszy, at the famed Washington University Medical School in Saint Louis tested the hypothesis that CR produces the same positive effects in humans as it does in laboratory animals. It compared serious CR practitioners with age-and sex-matched controls. The results have been widely reported in the medical literature.
Calorie Restriction Research project: Current investigators:
Luigi Fontana, M.D., Ph.D. (http://geriatrics.im...ty/fontana.html).
Dr. Fontana has gained special insights on human health from his experience as a practicing physician and as a researcher in metabolism. His passion is the science of aging. Dr. Fontana has already made medical history with the first phase of the project by showing that calorie restriction does indeed have age-slowing effects in humans.
The results have been reported worldwide in the medical literature:
We are now in phase 3, which continues the clinical testing – providing more data for the longitudinal analysis. Phase 3 also looks at the genetic effects of long-term CR in humans. We eagerly await the test results from Doctor Fontana to find out how serious, long-term CR affects cell signaling.
Meanwhile two other exciting human CR projects have been launched and rapidly move forward.
1. Cell Signaling exploration with genetic experts, Doctors, Stephen Spindler and Joseph Dhahbi.
Drs Dhahbi and Spindler, whose genetic analysis of calorie-restricted animals garners worldwide acclaim, lead the exploration of the microRNAs of human calorie restrictors in a new phase of the Calorie Restriction Project. Building on years of studying calorie restriction in animals, Drs. Spindler and Dhahbi will provide an incisive look into how calorie restriction affects genetic expression in calorie-restricted humans.
For those interested in knowing more about their work, take a look at these two research papers that report on the genetic expression patterns of calorie-restricted animals:
2, The Society is honored to partner with the CR Way on
CRONA (Caloric Restriction With Optimal Nutrition & Aging)– a milestone study that Looks at The Genetic Effects Of Caloric restriction from a different perspective , focusing on telomerase, telomere length and many other markers in a cohort of long-term serious calorie restrictors.
Headed by Dr. A. Janet Tomiyama at the University of Rutgers, the project includes:
Elizabeth Blackburn (, Nobel prize winner, Biochemistry & Biophysics, UCSF)
Anne Brunet (Dept of Genetics, Stanford)
Elissa Epel (Psychiatry, UCSF)
Pankaj Kapahi (Buck Institute for Age Research)
Cynthia Kenyon, (Biophysics and Biochemistry, UCSF)
Jue Lin (Biochemistry & Biophysics, UCSF)
Eric Verdin (Gladstone Institute of Virology and Immunology at UCSF)
Meredith Averill and Paul McGlothin thank Drs. John Holloszy and Luigi Fontana
Think of where we were in 2002, before the Society's research involvement began. There was little proof that CR really worked in humans. Now the results of the CR Research project provide tantalizing evidence that CR has profound health-enhancing and age-slowing benefits in humans. Indeed, the research results have been reported around the world – influencing the direction of additional research and providing vital guidance for anyone interested in better health.
Although there are many opinions about the best ways to practice CR, we all agree that there isn't a second to lose in pursuing research that will help us understand how to slow aging and prevent the diseases that so frequently come with getting older.
New Research projects
In addition to the current research project, the Society seeks additional collaborations that will stop the ravages of aging and extend healthy lifespan. We welcome contact from interested researchers and supporters who believe that not a minute should be lost in pursuing answers that will help us all live longer and better.
Of particular interest:
Please Contact: firstname.lastname@example.org
On behalf of the Society, the investigators and millions who have already benefited, I express a heartfelt thanks to the donors who make the research possible we couldn’t do it without you!
If you haven’t already contributed to the research, consider making an investment that is priceless: Help the Society research project reveal more about slowing aging – what works and what doesn't, so that we can all put it to use. Please make a tax-deductible contribution to the Society. You may use our donation page at https://www.crsociety.org/donate or send your donation to the Managing Director Bob Cavanaugh at the Calorie Restriction Society, 187 Ocean Drive, Newport, NC 28570. Be sure to write "CR Research" in the memo line to avoid confusion.
Stock investors can make their stocks purchases generate considerable tax benefits by donating them to the Society.