Alex K Chen Posted April 20 Report Share Posted April 20 https://www.neurology.org/doi/10.1212/WNL.0000000000209201 Quote Link to comment Share on other sites More sharing options...
mccoy Posted April 20 Report Share Posted April 20 3 hours ago, InquilineKea said: https://www.neurology.org/doi/10.1212/WNL.0000000000209201 Interesting study according to which the benefits of coffee in PD are mediated by caffeine mainly and not other compounds. Evidently, if the hypothesis of this study is valid, caffeine would try and restore some balance in the neurotransmitter system, like a dopaminergic effect and an anticholinergic effect. Quote Link to comment Share on other sites More sharing options...
mccoy Posted April 20 Report Share Posted April 20 In addition to all the above, coffee seems to contain significant amounts of the beneficial compounds: Chlorogenic acids https://pubmed.ncbi.nlm.nih.gov/36576278/#:~:text=It plays a role in,5 to 1000 mg%2Fd. Quote Link to comment Share on other sites More sharing options...
mccoy Posted April 20 Report Share Posted April 20 Trigonelline https://www.nature.com/articles/s42255-024-00997-x Quote Link to comment Share on other sites More sharing options...
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