TomBAvoider Posted September 18, 2023 Report Share Posted September 18, 2023 (edited) Metformin's claimed effects in healthy (i.e. non-diabetic) humans have certainly been full of twists, turns and reversals. Extends life, cuts down on cancer; no it doesn't and not in non-diabetics. Blunts or eliminates the benefits of exercise, poor effects on vo2max and muscle training. Latest plot twist: attenuates muscle atrophy (in the immobilized), generally slows the senescence of muscle tissues and keeps those cells young in older people: https://onlinelibrary.wiley.com/doi/10.1111/acel.13936 Stay tuned, I'm sure another 180 is just around the corner. Edited September 18, 2023 by TomBAvoider Quote Link to comment Share on other sites More sharing options...
Ron Put Posted September 18, 2023 Report Share Posted September 18, 2023 Very short-term. I am not sure how significant the differences are. Or, what other confounding factors there were. I am not sure if it's relevant, but it likely is, that some of the participants had A1C 5.9 which is rather high, and most were stage A obese. Importantly, I didn't notice insulin data mentioned. Quote Link to comment Share on other sites More sharing options...
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