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Muscle mass and heart disease


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Yes, the study suggests a significant association between myopenia and CV disease. Best way to avoid myopenia is by stimulation of the mechanogrowth factor (a form of local IGF-1) by weightlifting (and ingestion of enough nutrients).

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https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2788244
urolithin A is a supplement that appears to be beneficial for cell mitochondria by slowing muscle deterioration with age. Urolithin a is natura substance found in berries and wine.

Findings  In this randomized clinical trial of 66 older adults, those who received supplementation with 1000 mg of urolithin A had a significant improvement in muscle endurance (number of muscle contractions until fatigue) for both hand and leg skeletal muscles compared with those who used placebo. Plasma levels of several acylcarnitines, ceramides (biomarkers of mitochondrial health), and C-reactive protein were decreased after urolithin A supplementation.

Edited by Mike41
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I'm so friggin' cynical!  Lol!

 

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Conflict of Interest Disclosures:

Dr Liu reported receiving grants from drugs at no cost for research use from Stealth BioTherapeutics and supplements at no cost for research use from AstaReal outside the submitted work. Dr D'Amico reported being an employee of Amazentis SA during the conduct of the study and receiving personal fees from Amazentis SA outside the submitted work. Dr Shankland reported receiving drugs at no cost for research use from Stealth BioTherapeutics and supplements at no cost for research use from AstaReal outside the submitted work. Ms Bhayana reported receiving drugs at no cost for research use from Stealth BioTherapeutics and supplements at no cost for research use from AstaReal outside the submitted work. Dr Garcia reported being a full-time employee of the US government during the conduct of the study. Dr Aebischer reported being the chair of the board and a shareholder of Amazentis SA during the conduct of the study. Dr Rinsch reported being the founder, the chief executive officer, and a board member of Amazentis SA during the conduct of the study; holding a patent for US 9,872,850 issued, a patent for US 10,028,932 issued, a patent for US 10,485,782 issued, a patent for US 11,020,373 issued, a patent for US 10,906,883 issued, a patent for US 20180256538 pending, and a patent for US 20180256539 pending. Dr Singh reported being an employee of Amazentis SA during the conduct of the study and holding a patent for US 20180256538 pending and a patent for US 20180256539 pending. Dr Marcinek reported receiving drugs at no cost for research use from Stealth BioTherapeutics, grants from Boehringer Ingelheim, and supplements at no cost for research use from AstaReal outside the submitted work.

Funding/Support: This research was supported by Amazentis SA.

 

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Amazentis announces new clinical findings and launches first consumer product with Mitopure (proprietary highly pure Urolithin A) in the USA.  

Amazentis is an innovative life science company dedicated to employing breakthrough research and clinical science to bring advanced therapeutic nutrition products to life.

We employ rigorous science [ oh yeah!]  to pioneer the discovery and clinical development of the next generation of naturally derived bioactives, starting with Mitopure™ (a proprietary highly pure Urolithin A).

 Our focus is the development of innovative products designed to meet the health needs of an aging population. Our current work builds on modulating Mitochondrial function.

https://www.amazentis.com/

 

 

I'm sticking with elderberry wine for now!

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